Leo J. Pallanck, Ph.D. Professor of Genome Sciences Research Affiliate, Center on Human Development and Disability pallanck@genetics.washington.edu 206-616-5997 University of Washington Box 355065 Seattle, WA 98195-5065

Dr. Pallanck's laboratory uses the fruit fly Drosophila melanogaster as a genetic model system to understand the mechanisms underlying neurodegenerative disorders, such as Parkinson’s disease. Flies are a terrific system for this work because of the many powerful genetic tools that have been developed over the long history of their use as a model organism, and because recent work has established that neurodegenerative disorders can be successfully modeled using flies. At present, the Pallanck laboratory is pursuing three different projects: (1) Mitochondrial quality control; (2) Functional analysis of the glucocerebrosidase (GBA) gene; and (3) Traumatic brain injury.

University of Washington • Center on Human Development and Disability • Box 357920 • Seattle WA 98195-7920 USA • 206-543-7701 • chdd@uw.edu

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