Research
Emphasis Areas

Research Affiliates

Core Services
Behavioral Science Core

Brain Imaging Core

Cellular Morphology Core

Genetics Core

Infant Primate Research Laboratory Core

Instrument Development Laboratory Core

Nicholas Poolos, M.D., Ph.D.

Associate Professor of Neurology
Research Affiliate, Center on Human Development and Disability
npoolos@u.washington.edu
206-341-5423
University of Washington, Box 356560
Seattle, WA 98195-6560

Dr. Poolos studies epilepsy, one of the most common causes of neurological disability in children. Current treatments do not reliably prevent seizures and associated neuronal damage in about 25 percent of individuals with epilepsy. In particular, Poolos and his colleagues study links between epilepsy and neuronal ion channel dysfunction. Dysfunctional ion channels can cause hyperexcitability in neurons, which in turn produces seizures. The team hopes to discover new molecular targets for antiepileptic drugs by dissecting the signaling pathways underlying ion channel dysfunction in epilepsy.

Nicholas Poolos's web page

University of Washington • Center on Human Development and Disability Box 357920 • Seattle WA 98195-7920 USA • 206-543-7701 •chdd@u.washington.edu