Department of Chemistry
Ganessan, K., Napawan Ponmee, N., Jiang, L., Fowble, J., White, J., Kamchonwongpaisan, S., Yuthavong, Y., Wilairat, P., and Rathod, P.K. 2008 “A Genetically Hard-wired Metabolic Transcriptome in Plasmodium falciparum Fails to Mount Protective Responses to Lethal Antifolates”, PLoS Pathogens, 4(11): e1000214. PMC2581438
Gonzales, J.M., Patel, J.J., Ponmee, N., Jiang, L., Tan, A., Maher, S.P., Wuchty, S., Rathod, P.K., and Ferdig, M.T. 2008. Regulatory Hotspots in the Malaria Parasite Genome Dictate Transcriptional Variation. PLoS Biol 6(9): e238 PMC2581438
Antia, M., Herricks, T., and Rathod, P.K. 2008 “Microfluidic models for Malaria Pathogenesis (Invited Review)”, Cell. Microbiol., 10(10):1968-74. PMID18754851
Phillips, M.A., Gujjar, R., Malmquist, N.A., White, J., El Mazouni, F., Baldwin, J., and Rathod, P.K. 2008. “Triazolopyrimidine-based dihydroorotate dehydrogenase inhibitors with potent and selective activity against the malaria parasite, Plasmodium falciparum”, J. Med. Chem. 51:3649-53.PMC2624570
Hunter, J.H., Gujjar, R., Pang, C.K.T., and Rathod, P.K. 2008. “Kinetics and Ligand-Binding Preferences of Mycobacterium tuberculosis Thymidylate Synthases, ThyA and ThyX”. PLoS One 3(5): e2237. PMC2386288
Antia, M., Herricks, T., and Rathod, P.K. 2007 “Microfluidic modeling of cell-cell interactions in malaria pathogenesis”, PloS Pathogens, 3:e99. PMC1924869
Mudeppa, D.G., Pang , C.K.T., Tsuboi, T., Endo, Y., Buckner, F.S., Varani, G., and Rathod, P.K. 2007 “Cell-free production of functional Plasmodium falciparum dihydrofolate reductase-thymidylate synthase” Mol. Biochem. Parasitol., 151, 216-219
Shelby, J.P., White, J., Ganesan, K., Rathod, P.K., and Chiu, D.T. 2003. “A microfluidic model for single-cell capillary obstruction by Plasmodium falciparum-infected erythrocytes”, Proc. Natl. Acad. Sci. (USA), 100, 14618-14622.
Rathod, P.K. and Phillips, M.A 2003. “Prized malaria drug target nailed”, Nature Struct. Biol. 10, 316 – 318.
Zhang, K. and Rathod, P. K. 2002 “Divergent regulation of dihydrofolate reductase between malaria parasite and human host”, Science, 296, 545-547.
Rathod, P.K., Ganesan, K., Hayward, R.E., Bozdech, Z., and DeRisi, J. L. 2002 "DNA Microarrays for Malaria", Trends in Parasitology, 18, 39-45.
Hayword, R., DeRisi, J., Alfadhli, S., Kaslow, D., Brown, P., and Rathod, P.K. 2000 “Shotgun DNA microarrays and stage-specific gene expression in Plasmodium falciparum malaria”, Mol. Microbiol., 35, 6-14.
Rathod, P. K. and McErlean, T., and Lee, P-C. 1997 "Variation in frequency of drug resistance in Plasmodium falciparum", Proc. Natl. Acad. Sci. (USA), 94, 9389-9393.
Laur, S. A. , Rathod, P. K., Ghori, N. and Haldar, K. 1997 "A membrane network for nutrient transport in red cells infected with the malaria parasite", Science, 276, 1122-1125.
Gomez, Z. M., and Rathod, P. K. 1990. "Antimalarial activity of a 5-fluoroorotate and uridine combination in mice". Antimicrob. Agents. Chemother. 34: 1371-1375.
Rathod, P. K., Khatri, A., Hubbard, T., and Milhous, W. K.. 1989. "Selective activity of 5-fluoroorotate against Plasmodium falciparum in vitro". Antimicrob. Agents. Chemother. 33: 1090-1094.
Reyes, P., Rathod, P. K., Sanchez, D. J., Mrema, J. E. K., Riekman, K. H.,and Heidrich, H. -G. 1982. "Activities of purine and pyrimidine metabolizing enzymes of the human malarial parasite, Plasmodium falciparum". Mol. Biochem. Parasitol. 5: 275-290.
Back to Research Interest
Back to Research Interests
Molecular, Cellular, and Immunology of Parasites Award, ASTMH
Senior Scholar, Ellison Medical Foundation
Biology of Parasitism Course, Woods Hole, MA
New Initiatives in Malaria Research Award, Burroughs Wellcome Fund
Annual visiting lecturer, Biochemistry, Stanford University Medical Center, CA.
Research Career Development Award (RCDA), NIH
First Independent Research Support and Transition (FIRST) AWARD, NIH