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Thomas G. Spiro

Representative Publications

A conformational switch to beta-sheet structure in cytochrome c leads to heme exposure. Implications for cardiolipin peroxidation and apoptosis” Gurusamy Balakrishnan, Ying Hu, Oyeyemi F. Oyerinde, Jia Su, John T. Groves, and Thomas G. Spiro; J. Am. Chem. Soc., (2007), 129, 504 – 505.

“Differential Sensing of Protein Influences by NO and CO Vibrations in Heme Adducts” Mohammed Ibrahim, Changliang Xu, and Thomas G. Spiro; J. Am. Chem. Soc., (2006), 128, 16834 – 16845.

“Microsecond Melting of a Folding Intermediate in a Coiled-Coil Peptide, Monitored by T-jump/UV Raman Spectroscopy” Gurusamy Balakrishnan, Ying Hu, Martin A. Case, and Thomas G. Spiro; J. Phys. Chem. B., (2006), 110, 19877-19883.

"Heme Displacement Mechanism of CooA Activation: Mutational And Raman Spectroscopic Evidence” Mohammed Ibrahim, Robert L. Kerby, Mrinalini Puranik, Ingar H. Wasbotten, Hwan Youn, Gary P. Roberts, and Thomas G. Spiro; Journal of Biological Chemistry, (2006), 281, 29165–29173.

“Modeling of Ligation-Induced Helix/Loop Displacements in Myoglobin: Toward an understanding of Hemoglobin Allostery” Victor Guallar, Andrzej A. Jarzecki, Richard A. Friesner and Thomas G. Spiro; J. Am. Chem. Soc., (2006), 128, 5427-5435.

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Awards & Activities

ACS Award for Distinguished Service in the Advancement of Inorganic Chemistry, 2005

Biophysical Society Founders Award, 2005

Co-chair, Gordon Conference on Environmental Bio-inorganic Chemistry, 2004

Wellcome Visiting Professor in the Basic Medical Sciences, Univ. of British Columbia, 2000

Editorial Boards: Inorganic Chemistry (1988-90), Protein Science (1992 - 1995), Issues in Environmental Science and Technology (1994- ), BioSpectroscopy (1995- ), Inorganic Biochemistry (1997- )

Co-chair, NSF Workshop on Environmental Chemistry, 1992

AAAS Fellow, 1991

NIH MERIT Award, 1989

Guggenheim Fellow, 1989

Chair, Fourth International Conference on Time-Resolved Vibrational Spectroscopy, Princeton, 1989

Chair, Bioinorganic Subdivision, American Chemical Society, 1988

Bomem-Michelson Award, 1986

Biophysical Society Council, 1986-1989

International Steering Committee for the International Conference on Raman Spectroscopy (ICORS) 1982 - 1992

Eugene Higgins Chair of Chemistry, Princeton University,1981

Dreyfus Distinguished Lecturer, Furman University, 1981

Chair, Gordon Conference on Metals in Biology, 1978

NIH Metallobiochemistry Study Section, 1977-1979

NATO Senior Fellowship, 1972

NIH Postdoctoral Fellowship, 1962-1963

Fulbright Fellowship, 1960-1961

Sigma Xi

Phi Beta Kappa