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University of Washington Department of Chemistry Department of Chemistry

Robert E. Synovec

 

Representative Publications

“Comprehensive Analysis of Yeast Metabolite GCxGC-TOFMS Data: Combining Discovery-Mode and Deconvolution Chemometric Software,” R. E. Mohler, K. M. Dombek, J. C. Hoggard, K. M. Pierce, E. T. Young and R. E. Synovec, Analyst, 2007,132, 756.

“Investigation of High-Speed Chromatography using Synchronized Dual-Valve Injection and Resistively Heated Temperature Programming,” V. R. Reid, A. D. McBrady and R. E. Synovec, J. Chromatogr. A, 2007, 1148, 236.

“Unsupervised Parameter Optimization for Automated Retention Time Alignment of Severely Shifted Gas Chromatographic Data using the Piecewise Alignment Algorithm,” K. M. Pierce, B. W. Wright and R. E. Synovec, J. Chromatogr. A, 2007, 1141, 106.

“Analysis of Bacteria by Pyrolysis Gas Chromatography-Differential Mobility Spectrometry and Isolation of Chemical Components with a Dependence on Growth Temperature,” S. Prasad, K. M. Pierce, H. Schmidt, J. V. Rao, R. Güth, S. Bader, R. E. Synovec, G. B. Smith and G. A. Eiceman, Analyst, 2007, 10, 1031.

“Observations on “Orthogonality” in Comprehensive Two-Dimensional Separations,” N. E. Watson, J. M. Davis and R. E. Synovec, Anal. Chem., 2007, 79, 7924.

“Size-Exclusion Chromatography with Dual-Beam Refractice Index Detection of Polystyrene Samples,” E. M. Humston, A D. McBrady, M. Valero and R. E. Synovec, Talanta, 2007, 73, 2878.

“An Absorbance-Based Micro-Fluidic Sensor for Diffusion Coefficient and Molar Mass Determinations,” A. D. McBrady, R. Chaniwas, A. K. Torgerson, K. Grudpan, and R.E. Synovec, Anal. Chim. Acta, 2006, 575, 151.

“Classification of High Speed GC-MS Data by PCA Coupled with Piecewise Alignment and Feature Selection,” N. E. Watson, M. M. VanWingerden, K. M. Pierce, B. W. Wright and R. E. Synovec, J. Chromatogr. A, 2006, 1129, 111.

“Fisher Ratio Method Applied to Third Order Separation Data to Identify Significant Chemical Components of Metabolite Extracts,” K. M. Pierce, J. C. Hoggard, J. L. Hope, P. M. Rainey, A. N. Hoofnagle, R. M. Jack, B. W. Wright and R. E. Synovec, Anal. Chem., 2006, 78, 5068.

“Flow Injection Analysis with Diode Array Absorbance Detection and Dynamic Surface Tension Detection for Studying Denaturation and Surface Activity of Globular Proteins,” E. Bramanti, C. Allegrini, M. Onor, G. Raspi, K. J. Skogerboe and R. E. Synovec, Anal. Biochem., 2006, 351, 100.

“Microfabricated Refractive Index Gradient Based Detector for Reversed-Phase Liquid Chromatography with Mobile Phase Gradient Elution,” A. D. McBrady and R. E. Synovec, J. Chromatogr. A, 2005, 1105, 2.

“Classification of Gasoline Data Obtained by Gas Chromatography using a Piecewise Alignment Algorithm combined with Feature Selection and Principal Component Analysis,” K. M. Pierce, J. L. Hope, K. J. Johnson, B. W. Wright and R. E. Synovec, J. Chromatogr. A, 2005, 1096, 101. 

“A Comprehensive Two-Dimensional Retention Time Alignment Algorithm to Enhance Chemometric Analysis of Comprehensive Two-Dimensional Separation Data,” K. M. Pierce, L. F. Wood, B. W. Wright and R. E. Synovec, Anal. Chem., 2005, 77, 7735.

“High Throughput Screening of Protein Surface Activity via Flow Injection Analysis – pH Gradient – Dynamic Surface Tension Detection,” B. A. Staggemeier, E. Bramanti, C. Allegrini, K. J. Skogerboe and R. E. Synovec, Anal. Chem., 2005, 77, 250.

“High-Speed GC using Synchronized Dual-Valve Injection,” G. M. Gross, B. J. Prazen, J. W. Grate and R. E. Synovec, Anal. Chem., 2004, 76, 3517.

“Theoretical Modeling and Experimental Evaluation of a Microscale-Molecular Mass Sensor,” C. D. Costin, A. D. McBrady, M. E. McDonnell and R. E. Synovec, Anal. Chem., 2004, 76, 2725.

“Monolayer-Protected Gold Nanoparticles as an Efficient Stationary Phase for Open Tubular Gas Chromatography using a Square Capillary: A Model for Chip-Based GC in Square Cornered Microfabricated Channels,” G. M. Gross, J. W. Grate and R. E . Synovec, J. Chromatogr. A, 2004, 1029, 185.

“Trilinear Chemometric Analysis of Two-Dimensional Comprehensive Gas Chromatography Time-of-Flight Mass Spectrometry Data,” A. E. Sinha, C. G. Fraga, B. J. Prazen and R. E. Synovec, J. Chromatogr. A, 2004, 1027, 269.

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Awards & Activities

Editorial Board, Journal of Chromatography A, 2003 - present

Associated Editor, TALANTA, 1992 - present

Amersham Pharmacia Professor in Residence, Molecular Dynamics, 2000

Visiting Faculty, Royal Golden Jubilee Ph.D. Program, Chiang Mai University, Chiang Mai, Thailand, 1999

DuPont Educational Aid Grant, DuPont, 1999

Excellence in Graduate Research Award, Iowa State University, 1986

Phillips Petroleum Fellowship in Analytical Chemistry, Iowa State University, 1985 - 1986

ACS Fellowship, ACS Division of Analytical Chemistry, 1984

Alpha Chi Sigma Graduate Research Award in Analytical Chemistry, Iowa State University, 1984