Jesse G. Zalatan

Jesse Zalatan. Assistant Professor of Chemistry (starting September 2014)
Ph.D. Stanford University, 2008

(Biological Chemistry, Enzymology)



Research Interests

Description of research program forthcoming


Representative Publications

Zalatan, J.G.,* Coyle, S.M.*, Rajan, S., Sidhu, S.S., Lim, W.A. "Conformational control of the Ste5 scaffold protein insulates against MAP kinase misactivation.” Science 2012, 337, 1218-1222.

Lassila, J.K.,* Zalatan, J.G.,* Herschlag D. “Biological phosphoryl-transfer reactions: Understanding mechanism and catalysis.” Annu. Rev. Biochem. 2011, 80, 669-702.

Zalatan, J.G., Fenn, T.D., Herschlag, D. “Comparative enzymology in the alkaline phosphatase superfamily to determine the catalytic role of an active site metal ion.” J. Mol. Biol. 2008, 384, 1174-1189.

Zalatan, J.G., Fenn, T.D., Brunger, A.T., Herschlag, D. “Structural and functional comparisons of nucleotide pyrophosphatase/phosphodiesterase and alkaline phosphatase: Implications for mechanism and evolution.” Biochemistry 2006, 45, 9788-9803.

Zalatan, J.G., and Herschlag, D. “Alkaline phosphatase mono- and diesterase reactions: Comparative transition state analysis.” J. Am. Chem. Soc. 2006, 128, 1293-1303.


Awards & Activities

2012-2016 Burroughs Wellcome Career Award at the Scientific Interface

2009-2011 Damon Runyon Postdoctoral Fellowship

2002-2007 Hertz Foundation Graduate Fellowship


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