Final Examination – Dissertation Defense

Congratulations to Thomas Chung, who defended his Ph.D. work “Toward a Fundamental Basis for Understanding Electron-Based Methods of Peptide Dissociation” on February 22. He was a student in Professor Frank Turecek’s laboratory for the past 3.5 years. He currently works at Baylor University as a postdoctoral research associate for Dr. Bryan F. Shaw in the Department of Chemistry & Biochemistry. Thomas’s research at Baylor University sits at the interface of bioanalytical chemistry, medicine, and structural biology.  He endeavors in the Shaw Lab to develop new therapeutics to treat protein aggregation diseases like amyotrophic lateral sclerosis (ALS, a.k.a. Lou Gehrig’s disease), cataracts, and type 2 diabetes.  Thomas also carries out efforts in instrumentation development, especially in the area of capillary electrophoresis-mass spectrometry (CE-MS).  He uses said tools in order to elucidate the structure of proteins, e.g., ALS-variant superoxide dismutase 1 (SOD1), at the proteomic level.  Another of his new research thrusts involves determining how the electrostatic surface potential of proteins influences their rate of amide hydrogen-deuterium exchange (HDX).

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