Recent Publications in Respiratory, Autonomic and Sleep

 

Allen T, Juric-Sekhar G, Campbell S, Mussar KE, Seidel K, Tan J, Zyphur M, Villagracia L, Stephanian D, Koch H, Ramirez JM, Rubens DD. (2010). Inner ear insult suppresses the respiratory response to carbon dioxide. Neuroscience. Feb 23;175:262-72

Carroll MS, Kenny AS, Patwari PP, Ramirez JM, Weese-Mayer DE. (2012). Respiratory and cardiovascular indicators of autonomic nervous system dysregulation in familial dysautonomia. Pediatr Pulmonol. 2012 Jul;47(7):682-91. doi: 10.1002/ppul.21600. Epub 2011 Dec 13.

Crone S, Viemari JC, Droho S, Mrejeru A, Ramirez JM, Sharma K (2012). Irregular breathing in mice following genetic ablation of V2a neurons. J. Neuroscience Jun 6;32(23):7895-906.

Doi A, Ramirez JM. (2010). State-dependent interactions between excitatory neuromodulators in the neuronal control of breathing. J. Neuroscience 30(24): 8251-62.  PMID: 20554877

Garcia AJ 3rd, Khan SA, Kumar GK, Prabhakar NR, Ramirez JM. (2011) Hydrogen peroxide differentially affects activity in the preBotzinger Complex and hippocampus. J Neurophysiol. 106(6):3045-55

Hill AA, Garcia AJ 3rd, Zanella S, Upadhyaya R, Ramirez JM. (2011). Graded reductions in oxygenation evoke graded reconfiguration of the isolated respiratory network. J Neurophysiol. Feb;105(2):625-39.

Koch H, Garcia AJ 3rd, Ramirez JM. (2011). Network Reconfiguration and Neuronal Plasticity in Rhythm-Generating Networks. Integr Comp Biol. 2011 51 (6): 856-868.

Madisen L, Mao T, Koch H, Zhuo J, Berenyi A, Shigeyoshi F, Hsu YWA, Garcia III AJ, Gu X, Zanella S, Mao Y, Hooks BM, Boyden ES, Buzsaki G, Ramirez JM,  Jones AR, Svoboda K, Han X, Turner E, Zeng H (2012) Toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing. Nature Neuroscience 15(5):793-802.

Quintana A, Zanella S, Koch H, Kruse S, Lee D., Ramirez JM, Palmiter RD. (2012). Fatal breathing dysfunction in a mouse model of Leigh Syndrome. J. Clinical Investigation. Jun 1. pii: 62923. doi: 10.1172/JCI62923.

Tryba AK, Peña F, Lieske SP, Viemari JC, Thoby-Brisson M, Ramirez JM. (2008). Differential modulation of neural network and pacemaker activity underlying eupnea and sigh-breathing activities. J Neurophysiol. 99(5):2114-25.

Viemari JC, Garcia III AJ, Doi A, Ramirez JM (2011). Activation of alpha-2 noradrenergic receptors is critical for the generation of fictive eupnea and fictive gasping inspiratory activities in mammals in vitro. European J. Neuroscience Jun;33(12):2228-37.

Weese-Mayer DE, Lieske SP, Boothby CM, Kenny AS, Bennett HL, Ramirez JM. (2008). Autonomic dysregulation in young girls with Rett Syndrome during nighttime in-home recordings. Pediatric Pulmonology, 43 (11): 1045-1060.

Weese-Mayer DE, Kenny AS, Bennett HL, Ramirez JM, Leurgans SE (2008). Familial Dysautonomia:  Frequent, Prolonged and Severe Hypoxemia during Wakefulness and Sleep. Pediatric Pulmonology 43(6):624-625.

 

Other select papers:

Lieske SP, Ramirez JM.  Effects of alterations in synapse strength.  J Neurophysiol. 2006 Mar;95(3):1323-33.

Lieske SP, Ramirez JM. Pattern-specific synaptic mechanisms in a multifunctional network. II. Intrinsic modulation by metabotropic glutamate receptors. J Neurophysiol. 2006 Mar;95(3):1334-44.

Lieske SP, Thoby-Brisson M, Telgkamp P, Ramirez JM. (2000). Reconfiguration of the neural network controlling multiple breathing patterns: eupnea, sighs and gasps. Nature Neuroscience 3(6): 600-607.

Peña F, Ramirez JM.  Hypoxia-induced changes in neuronal network properties.  Mol Neurobiol. 2005 Dec;32(3):251-83. Review.

Pena F, Parkis MA, Ramirez JM. (2004). Differential contribution of pacemaker properties to the generation of respiratory rhythms during normoxia and hypoxia. Neuron, 43: 105-117.

Ramirez JM, Viemari JC.  Determinants of inspiratory activity.  Respir Physiol Neurobiol. 2005 Jul 28;147(2-3):145-57. Review.

Tryba AK, Peña F, Ramirez JM. Gasping activity in vitro: a rhythm dependent on 5-HT2A receptors.. J Neurosci. 2006 Mar 8;26(10):2623-34.

Viemari JC, Roux JC, Tryba AK, Saywell V, Burnet H, Peña F, Zanella S, Bévengut M, Barthelemy-Requin M, Herzing LB, Moncla A, Mancini J, Ramirez JM, Villard L, Hilaire G.  Mecp2 deficiency disrupts norepinephrine and respiratory systems in mice.  J Neurosci. 2005 Dec 14;25(50):11521-30.

Viemari JC, Ramirez JM.  Norepinephrine differentially modulates different types of respiratory pacemaker and nonpacemaker neurons.  J Neurophysiol. 2006 Apr;95(4):2070-82. Epub 2006 Jan 4

Weese-Mayer DE, Lieske SP, Boothby CM, Kenny AS, Bennett HL, Silvestri JM, Ramirez JM.  Autonomic nervous system dysregulation: breathing and heart rate perturbation during wakefulness in young girls with Rett syndrome.  Pediatr Res. 2006 Oct;60(4):443-9. Epub 2006 Aug 28.

Reviews:

Doi A, Ramirez JM. (2008). Neuromodulation and the orchestration of the respiratory rhythm. Respir Physiol Neurobiol. 2008 Jun 12.

Garcia III A, Zanella S, Koch H, Doi A. (2011). Networks within Networks: The neuronal Control of Breathing. Prog. In Brain Res. Vol 188: 31-50

Katz DM, Dutschmann M, Ramirez JM, Hilaire G. (2009). Breathing disorders in Rett syndrome: Progressive neurochemical dysfunction in the respiratory network after birth. Respir Physiol Neurobiol. Apr 24. PMID: 19394452.

Koch H, Garcia AJ 3rd, Ramirez JM. (2011). Network reconfiguration and neuronal plasticity in rhythm-generating networks. Integr Comp Biol. 2011 Dec;51(6):856-68. Epub 2011 Aug 19.

Ramirez JM, Koch H, Garcia III A,  Zanella S., (2011). The role of spiking and bursting pacemakers in the neuronal control of breathing. J. Biological Physics. Jun;37(3):241-61. Epub 2011 Mar 22.

Ramirez JM, Folkow LP, Blix AS. (2007). Mechanisms conveying hypoxic tolerance to birds and mammals. Annual Review of Physiology. 2007;69:113-43.

Ramirez JM. (2011). The human pre-Bötzinger complex identified. Brain, 134: 8-10.

Ramirez JM, Garcia III A, Doi A, Elsen FP, Wei A. (2012). Cellular Properties of Respiratory Brainstem Neurons. Comprehensive Physiology, Invited Review. Accepted

Rubens D, Davis A, McAlpine J, Fleming P, Blair P, Ewer A. Letter of Response to Chan et al.’s paper regarding Rhode Island Newborn Hearing screening finding and the Sudden Infant Death Syndrome. Int J Pediatr Otorhinolaryngol. 2013 Feb 8.