Hydrocephalus – Cerebellar malformations

 

Studies of cerebellar malformations have led to a more general interest in birth defects of the dorsal midline of the brain – including hydrocephalus, aqueductal stenosis, agenesis of the corpus callosum, chiari malformation and spina bidifa.  Collaborative efforts between Millen and Dobyns have led to defining the first causative genes for Dandy-Walker malformation.