Tech & Innovation Center – Classical Conditioning

CIBR supports multiple setups for classical conditioning of eyeblink reflexes to allow bidirectional research between clinical populations and experimental animals.  As a paradigm to assess associative learning, motor function, and rapid temporal processing, eyeblink conditioning is acknowledged to be one of the most useful models to assess thalamocortical and cerebellar functioning.  Classical conditioning setups are in place to perform eyeblink conditioning in mice and rats, for pure behavioral assessment or during electrophysiological recordings and optogenetic stimulation, and also for 1-month old human infants at the University of Washington Center on Human Development and Disability.  By using identical paradigms in non-human and human subjects, CIBR investigators have created a “common-currency” of functional testing that is allowing truly bidirectional research between the bench and the clinical laboratories.

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