Epilepsy
Epilepsy is one of the most common human neurological disorders, affecting up to 3% of the population. A multidisciplinary group of CIBR investigators and collaborators probe this disorder from the molecular, cellular level to systems neuroscience. Researchers in the departments of Pediatrics, Neurology, Neurological Surgery, Radiology, Engineering, Genetics and Computer Science collaborate on several projects. Epilepsy research is conducted in collaboration with the University of Washington Integrated Brain Imaging Center (IBIC), Seattle Children’s Hospital’s Interdepartmental Epilepsy Program, the University of Washington Regional Epilepsy Center, and collaborators from other institutions throughout the country and worldwide
CIBR Investigators:
- William B. Dobyns, MD
- Sidney M. Gospe, MD, PhD
- Franck Kalume, PhD
- Heather Mefford, MD
- Edward J. Novotny, MD
- Jeffrey Ojemann, MD
- Nino Ramirez, PhD
- William Shain, PhD
Current Projects:
- Neuronal Properties In Focal and Parafocal Regions in Intractable Neocortical Epilepsy of Pediatric Patients
- Homeostatic Plasticity, Inflammation and Epilepsy
- Sudden Unexplained Death of Epilepsy (SUDEP)
- Early-Life Seizures and Development of Gabaergic Inhibition in The Human Brain
- Electrocorticography
- DTI and fMRI in Temporal Lobe Epilepsy
- Career: Novel Optimization Methods for Cooperative Data Mining With Health-Care And Biotechnology Applications
- Epilepsy Phenome Genome Project
- EP14K: Gene Discovery in 4,000 Epilepsy Genomes
- A Genomic Approach to Epilepsy
- De Novo Copy Number Variation and Gene Discovery In Human Brain Malformations
- Pyridoxine-Dependent Epilepsy
- Bioimage Suite
Recent Publications in Epilepsy Click here