News and Events
Updates on the instrument reservation and usage protocols (07/17/13). Thank you for your continued patience and understanding during our instrument protocol revisions.
Currently registered users, please note that we are reactivating our previous instrument calendar system. Please discontinue use of the CORAL program to schedule instrument time. Instead, schedule instrument time using the link provided above.
New users need to register with John Sumida, the Core manager, to access instruments. Please see his contact information below.
Welcome to the Analytical Biopharmacy Core
Established in 2009 with funding from the Washington state Life Sciences Discovery Fund, the Analytical Biopharmacy Core ("the Core") serves the general research community at UW, the Fred Hutchinson Cancer Research Center, and regional biotechnology companies on a cost-per-use basis. This resource, which is administered within the Department of Medicinal Chemistry at The University of Washington in Seattle, provides biophysical instrumentation and expertise for the characterization of molecular interactions between biotherapeutic molecules and their receptors, metabolites, delivery vehicles, or any relevant biological components.
The specific aims for the Center include development of delivery platforms that enhance the efficiency of therapeutic proteins, peptides, and siRNA to reach the cytosolic compartment of cells. The biopharmacy core facility provides analytical expertise in several state-of-the-art biophysical methods including analytical ultracentrifugation, surface plasmon resonance, differential scanning calorimetry, and isothermal titrating calorimetry. Interested labs can submit samples for Core scientists to run. The Core also provides training to the Center for Intracelluar Delivery of Biologics (CIDB) and UW students and staff. The Core is supported through the CIDB by the UW School of Pharmacy and the Life Sciences Discovery Fund.
Using the Analytical Biopharmacy Core
Please note that as access to the Instrumentation labs is restricted, please use the courtesy phone located in the lobby to contact lab personnel for admittance.
To discuss your experimental needs, and to arrange for training and instrument time, please contact the Core Manager.
|Analytical Biopharmacy Core Contact Information|
|John Sumida, Ph.D.||Core Managerfirstname.lastname@example.org|
|William M. Atkins, Ph.D.||Directoremail@example.com|
|Hyewon Kwon||Staff Scientistfirstname.lastname@example.org|
|Michael J. Dabrowski||Research Scientistemail@example.com|
To schedule work, contact the Core manager (firstname.lastname@example.org). Scheduling work in the Analytical Biopharmacy Core is done through a calendaring system that resides on the CIDB website. Access to the calendaring system is accomplished with a password that is assigned after you meet with the Core manager.
Users must provide their own Series S sensor chips (for SPR work), buffers, reagents, and other materials specific for their work. The facility has very limited cold storage space; thus, sample storage must be limited to samples necessary for currently running experiments only. All buffer conditions and protein materials must meet the approval of the facility manager, and all solutions materials must be properly labeled.
Publishing Work Done in the Analytical Biopharmacy Core
Please acknowledge all work done on core facility instruments by citing the Analytical Biopharmacy Core, its contributing scientists, the School of Pharmacy and the Molecular Engineering and Sciences Institute at the University of Washington. Core personnel directly involved in performing and designing experiments should be considered for authorship.