News and Events
New instrument signup protocol coming soon. The Analytical Biopharmacy Core will be transitioning from our current instrument calendar system to CORAL, an instrument calendar program designed by the UW College of Engineering. Please familiarize yourselves with the new protocol, which will be activated in mid-June, 2013. The following CORAL links provide current users access to the instrument calendar and a registration protocol for new users. Please note that the Biacore T100 and T200 will be the first instruments to transition to the new calendar system. Thank you, in advance, for your patience and understanding during the instrument calendar transition.
AUC workshop.The Core will offer an Advanced Applied Analytical Ultracentrifugation Workshop featuring Dr. Thomas Laue, Dr. Walter Stafford and Dr. James Cole on September 30th - October 3rd, 2013.
Welcome to the Analytical Biopharmacy Core
The Analytical Biopharmacy Core ("the Core") serves the general research community at UW, the Fred Hutchinson Cancer Research Center, and regional biotechnology companies on a cost-per-use basis. This resource, which is administered within the Department of Medicinal Chemistry at The University of Washington in Seattle, provides biophysical instrumentation and expertise for the characterization of molecular interactions between biotherapeutic molecules and their receptors, metabolites, delivery vehicles, or any relevant biological components.
The specific aims for the Center include development of delivery platforms that enhance the efficiency of therapeutic proteins, peptides, and siRNA to reach the cytosolic compartment of cells. The biophysical core facility provides analytical expertise in several state-of-the-art biophysical methods including analytical ultracentrifugation, surface plasmon resonance, differential scanning calorimetry, and isothermal titrating calorimetry. Interested labs can submit samples for Core scientists to run. The Core also provides training to CIDB and UW students and staff. The Core is funded through the Center for Intracellular Delivery of Biologics ("CIDB"), which is administered in the Department of Bioengineering.
Please note that the Core has moved to room G22 in the Molecular Engineering and Sciences Institute (MolES) located at 3946 W Stevens Way NE. As access to the Instrumentation labs is restricted, please use the courtesy phone located in the lobby to contact lab personnel for admittance.
Using the Analytical Biopharmacy Core
Contacts
To discuss your experimental needs, and to arrange for training and instrument time, please contact the Core Manager.
Analytical Biopharmacy Core Manager
(main contact to schedule and coordinate work):
John Sumida, Ph.D.
206-616-3971
jpsumida@uw.edu
Associated Faculty and Scientists
William M. Atkins, Ph.D.
Medicinal Chemistry
206-685-3079
winky@uw.edu
Carlos E. Catalano, Ph.D.
Medicinal Chemistry
206-685-2468
catalanc@uw.edu
Michael J. Dabrowski
Medicinal Chemistry
206-616-2781
dabrowsk@uw.edu
Scheduling Work
To schedule work, contact the Core manager (jpsumida@uw.edu). Scheduling work in the Analytical Biopharmacy Core is done through a calendaring system that resides on the CIDBC website. Access to the calendaring system is accomplished with a password that is assigned after you meet with the Core manager.
Users must provide their own Series S sensor chips (for SPR work), buffers, reagents, and other materials specific for their work. The facility has very limited cold storage space; thus, sample storage must be limited to samples necessary for currently running experiments only. All buffer conditions and protein materials must meet the approval of the facility manager, and all solutions materials must be properly labeled.
Publishing Work Done in the Analytical Biopharmacy Core
Please acknowledge all work done on Core facility instruments by citing the Analytical Biopharmacy Core, its contributing scientists, the Center for Intracellular Delivery of Biologics, the Washington State Life Sciences Discovery Fund and the School of Pharmacy. Core personnel directly involved in performing and designing experiments should be considered for authorship. Citation templates are available here in PDF or MS Word format