Welcome to the Analytical Biopharmacy Core
The Analytical Biopharmacy Core ("the Core") serves the general research community at UW, the Fred Hutchinson Cancer Research Center, and regional biotechnology companies on a cost-per-use basis. This resource, which is administered within the Department of Medicinal Chemistry at The University of Washington in Seattle, provides biophysical instrumentation and expertise for the characterization of molecular interactions between biotherapeutic molecules and their receptors, metabolites, delivery vehicles, or any relevant biological components. The specific aims for the Center include development of delivery platforms that enhance the efficiency of therapeutic proteins, peptides, and siRNA to reach the cytosolic compartment of cells. The biophysical core facility provides analytical expertise in several state-of-the-art biophysical methods including analytical ultracentrifugation, surface plasmon resonance, differential scanning calorimetry, and isothermal titrating calorimetry. Interested labs can submit samples for Core scientists to run. The Core also provides training to CIDB and UW students and staff. The Core is funded through the Center for Intracellular Delivery of Biologics ("CIDB"), which is administered in the Department of Bioengineering.
Using the Analytical Biopharmacy Core
Contacts
To discuss your experimental needs, and to arrange for training and instrument time, please contact the Core Manager.
Analytical Biopharmacy Core Manager
(main contact to schedule and coordinate work):
John Sumida, Ph.D.
206-616-3971
jpsumida@uw.edu
Associated Faculty and Scientists
William M. Atkins, Ph.D.
Medicinal Chemistry
206-685-3079
winky@uw.edu
Carlos E. Catalano, Ph.D.
Medicinal Chemistry
206-685-2468
catalanc@uw.edu
Michael J. Dabrowski
Medicinal Chemistry
206-616-2781
dabrowsk@uw.edu
Scheduling Work
To schedule work, contact the Core manager (jpsumida@uw.edu). Scheduling work in the Analytical Biopharmacy Core is done through a calendaring system that resides on the CIDBC website. Access to the calendaring system is accomplished with a password that is assigned after you meet with the Core manager.
Users must provide their own Series S sensor chips (for SPR work), buffers, reagents, and other materials specific for their work. The facility has very limited cold storage space; thus, sample storage must be limited to samples necessary for currently running experiments only. All buffer conditions and protein materials must meet the approval of the facility manager, and all solutions materials must be properly labeled.
Publishing Work Done in the Analytical Biopharmacy Core
Please acknowledge all work done on Core facility instruments by citing the Analytical Biopharmacy Core, its contributing scientists, the Center for Intracellular Delivery Biologics and the Washington State Life Sciences Discovery Fund. Core personnel directly involved in performing and designing experiments should be considered for authorship.