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Publications

  1. Mahajan SS, Scian M, Sripathy S, Posakony J, Lao U, Loe TK, Leko V, Thalhofer A, Schuler A, Bedalov A, Simon JA. "Development of Pyrazolone and Isoxazol-5-one Cambinol Analogs as Sirtuin Inhibitors." Journal of Medicinal Chemistry (2014). [PubMed - in process]
  2. Wang Z, Wong T, Hashizume T, Dickmann LZ, Scian M, Koszewski NJ, Goff JP, Horst RL, Chaudhry AS, Shuetz EG, Thummel KE. "Human UGT1A4 and UGT1A3 Conjugate 25-Hydroxyvitamin D3: Metabolite Structure, Kinetics, Inducibility and Interindividual Variability." Endocrinology (2014).[PubMed link]
  3. Scian M, Acchione M, Li M, Atkins WM. "Reaction dynamics of ATP hydrolysis catalyzed by P-glycoprotein." Biochemistry (2014). [PubMed link]
  4. Collins MD, Gordon SE. "Short-Chain Phosphoinositide Partitioning into Plasma Membrane Models." Biophysical Journal (2013). [PubMed link]
  5. Tinberg CE, Khare SD, Dou J, Doyle L, Nelson JW, Schena A, Jankowski W, Kalodimos CG, Johnsson K, Stoddard BL, Baker D. "Computational design of ligand-binding proteins with high affinity and selectivity." Nature (2013). [PubMed link]
  6. Davenport TM, Guttman W, Guo W, Cleveland B, Kahn M, Hu SL, Lee KK. "Isolate-Specific Differences in the Conformational Dynamics and Antigenicity of HIV-1 gp120." J Virol. (2013). [PubMed link]
  7. Irons EE, Flatt JW, Doronin K, Fox TL, Acchione M, Stewart PL, Shayakhmetov DM. "Coagulation factor binding orientation and dimerization may influence infectivity of adenovirus-coagulation factor complexes." J Virol. (2013). [PubMed link]
  8. Doronin K, Flatt JW, Di Paolo NC, Khare R, Kalyuzhniy O, Acchione M, Sumida JP, Ohto U, Shimizu T, Akashi-Takamura S, Miyake K, Macdonald JW, Bammler TK, Beyer RP, Farin FM, Stewart PL, Shayakhmetov DM. "Coagulation Factor X Activates Innate Immunity to Human Species C Adenovirus." Science (2012). [PubMed link]
  9. Wang D, Robertson IM, Li MX, McCully ME, Crane ML, Luo Z, Tu AY, Daggett V,Sykes BD, Regnier M. "Structural and Functional Consequences of the CardiacTroponin C L48Q Ca(2+)-Sensitizing Mutation." Biochemistry (2012). [PubMed link]
  10. King NP, Sheffler W, Swaya MR, Vollmar BS, Sumida JP, André I, Gonen T, Yeats TO, Baker D. "Computational design of self-assembling protein nanomaterials with atomic level accuracy." Science (2012). [PubMed link]
  11. Scellini B, Ferrara C, Piroddi N, Sumida J, Poggesi C, Lehrer SS, Tesi C. "Tropomyosin D137L of Reduced Flexibility Increases Submaximal Ca2+-Activated Tension in Skeletal Muscle Myofibrils after Troponin-Tropomyosin Removal and Reconstitution." Biophysical Journal (2012).
  12. Acchione M, Kwon, HW, Jochheim, CM, Atkins WM. "Impact of Linker and Conjugation Chemistry on Antigen Binding, Fc Receptor Binding and Thermal Stability of Model Antibody-Drug Conjugates." mAbs (2012). [PubMed link]
  13. Shimshoni JA, Roberts AG, Scian M, Topletz AR, Blankert SA, Halpert JR, Nelson WL, Isoherranen N. "Stereoselective formation and metabolism of 4-Hydroxy-Retinoic acid enantiomers by cytochrome P450 enzymes." Journal of Biological Chemistry (2012). [PubMed link]
  14. Wang Z, Lin YS, Zheng. ZE, Senn T, Hashizume T, Scian M, Dickmann LJ, Nelson SD, Baillie TA, Hebert MF, Blough D, Davis CL, Thummel KE. "An Inducible cytochrome P450 3A4-dependent vitamin D catabolic pathway." Molecular Pharmacology (2012). [PubMed link]
  15. Guttman M, Scian M, Lee KK. "Tracking hydrogen/deuterium exchange at glycan sites in glycoproteins by mass spectrometry" Analytical Chemistry (2011). [PubMed link]
  16. Cheng F, Shang J, Ratner DM. "A versatile method for functionalizing surfaces with bioactive glycans." Bioconjug Chem. (2011). [PubMed link]
  17. Honaker MT, Acchione M, Sumida JP, Atkins WM. "Ensemble perspective for catalytic promiscuity: calorimetric analysis of the active site conformational landscape of a detoxification enzyme." J Biol Chem. (2011). [PubMed link]
  18. Ritchie T, Kwon H, Atkins WM. "Conformational Analysis of Human ATP-binding Cassette Transporter ABCB1 in Lipid Nanodiscs and Inhibition by the antibodies MRK16 and UIC2." J Biol Chem. (2011). [PubMed link]
  19. Thomas CJ, Briknarová K, Hilmer JK, Movahed N, Bothner B, Sumida JP, Tall GG, Sprang SR. "The nucleotide exchange factor Ric-8A is a chaperone for the conformationally dynamic nucleotide-free state of Gαi1." PLoS One (2011). [PubMed link]
  20. 55th annual Biophysical Society Meeting: poster presentation STUDENT TRAVEL AWARDEE 2011, David Yampolsky, John P. Sumida, Sherwin S. Lehrer. Effects of a disulfide crosslink on the trypsin cleavage pattern of rabbit cardiac tropomyosin.
  21. 55th annual Biophysical Society Meeting: platform 2011, Stephen R. Sprang, Celestine Thomas, Klara Bricknarova, John Sumida, Gregory Tall. Ric-8A catalyzed G protein activation proceeds through a disordered state.
  22. 54th annual Biophysical Society Meeting: platform 2010, Jasmine Nirody, Xiaochuan Li,Duncan Sousa, John Sumida, Stefan Fischer, Sherwin S. Lehrer, William Lehman. Electron Microscopy and molecular dynamics on D137L mutant of tropomyosin.
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    Please acknowledge all work done on core facility instruments by citing the Analytical Biopharmacy Core, its contributing scientists, the School of Pharmacy and the Molecular Engineering and Sciences Institute at the University of Washington. Core personnel directly involved in performing and designing experiments should be considered for authorship.

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