Dr. Dennis is a diplomate of the American College of Laboratory
Animal Medicine (ACLAM). His research interests have centered
on the development of implanted vascular catheters for long-term
blood access, sepsis associated with implanted catheters,
and development of animal models of human diseases. He developed
a model of uremia in sheep, studied rejection of transplanted
kidneys in dogs, devised a model of bleeding gastric ulcers
used to develop methods for hemostasis deliverable by endoscopy,
and developed models of sepsis associated with percutaneous
implants, using sheep and rabbits. In 1994-95, Dr. Dennis
spent one year at the NIH, as Acting Director of the intramural
Veterinary Resources Program. Upon his return to the UW, he
became the Chair of the Department of Comparative Medicine,
a position he held from July, 1995, until August, 2004. He
is the UW Attending Veterinarian. He has been active on the
UW Institutional Animal Care and Use Committee (IACUC) and
has participated in numerous programs for education of IACUC
members. He has an interest in the ethics of the use of animals
in research, teaching, and testing. He has published on the
use of alternatives to animals in teaching and the establishment
of humane endpoints for genetically modified animals.
Dr. Dennis has been a member of AVMA since 1961. He is a
member of the American Association of Laboratory Animal Science
(AALAS) and serves as Chair of its International Relations
Advisory Council. He is also the AALAS delegate to the International
Council for Laboratory Animal Science (ICLAS). He serves on
the ICLAS Governing Board and is Co-Chair of its Americas
Regional Committee. Dr. Dennis is a Past President of the
Academy of Surgical Research. He is a member of Scientists
Center for Animal Welfare (SCAW). He is on the Board of Directors
for the Northwest Association for Biomedical Research.
Dennis MB Jr: Welfare issues of genetically modified animals. ILAR J, 43(2):100-110, 2002.
Perret-Gentil MI, Sinanan MN, Dennis MB Jr, Anderson DM,
Pasieka HB, Weyhrich JT, Birkebak TA: Videoendoscopic techniques
for collection of multiple, serial intra-abdominal biopsy
specimens in HIV-negative and HIV-positive pigtail macaques
(Macaca nemestrina). J Invest Surg 13:181-195, 2000.
Dennis MB Jr: Humane endpoints for genetically engineered
animal models. ILAR J, 41(2):35-39, 2000.
Dennis MB Jr: Alternative training methods II: Incorporating
inanimate surgical models. Lab Animal, 28(5):32-36,
1999.
Dennis MB Jr: IACUC Review of Genetic Engineering Protocols.
IN: Genetic Engineering and Animal Welfare: Preparing for
the 21st Century. Whitney RA (ed). Scientists Center for Animal
Welfare, Greenbelt, MD, 1999, pp 20-31.
Dennis MB Jr: Protection of Research Animals. IN: Handbook
of Biomaterials Evaluation, second edition. vonRecum AF (ed)
Taylor & Francis, Washington, 1998, pp 465-473.
