School of Medicine University of Washington Seattle, WA 98195 Adjunct Associate Professor Department of Epidemiology School of Public Health University of Washington Seattle, WA 98195 Director of Animal Health Resources Fred Hutchinson Cancer Research Center P.O. Box 19024 Seattle, WA 98109 email: bweigler@fhcrc.org

Ben Weigler is the Director of the program of laboratory animal care and use at Fred Hutchinson Cancer Research Center. Dr. Weigler’s research is in the area of infectious disease epidemiology and public health, with concentration in zoonotic diseases. He also conducts population-based studies on occupational health and safety issues applicable to workplace environments that involve laboratory animals and their tissues. Some of his epidemiological research projects have included B virus of macaques, feline herpesvirus, koala chlamydial disease, rodent pasteurellosis, and canine hepatozoonosis. Dr. Weigler is a member of several professional veterinary medical organizations and is on the editorial board for the scientific journal Comparative Medicine. He recently served on the National Research Council (NRC) Committee on Occupational Health and Safety in Care and Use of Nonhuman Primates, the Institute of Medicine and NRC Committee on Accelerating the Research, Development, and Acquisition of Medical Countermeasures Against Biological Warfare Agents, and the steering committee for the Centers for Disease Control and Prevention and Eagleson Institute 7th National Biosafety Symposium. He is board-certified by the American College of Laboratory Animal Medicine and by the American College of Veterinary Preventive Medicine.

Selected Publications and Presentations

Yunusov MY, Kerbauy F, Abrams K, Zellmer E, Spector M, Kuhr CS, Hwang B, Storer B, Georges GE, Weigler BJ, Storb R, Nash RA . Intussusception in Canine Recipients of Hematopoietic Cell Grafts and Surgical Correction. Comparative Medicine 2007 ( In Press).

Lupu M, Sulllivan EW, Westfall TE, Little M-T, Weigler BJ, Moore PF, Stroup PA, Zellmer E, Kuhr C, Storb R. Use of multigeneration-family molecular dog leukocyte antigen typing to select a hematopoietic cell transplant donor for a dog with T-cell lymphoma. Journal of the American Veterinary Association 2006; 228(5):728-732.
Weigler BJ, Di Giacomo RF, Alexander S. A national survey of laboratory animal workers concerning occupational risks for zoonotic diseases. Comparative Medicine 2005;55:183-191

Benet LZ, Brandt WE, Coller BS, Crooks GM, Douglas RG, Gansler JS, Itteilag AL, Kasper DL, Kelman SJ, Kingham RF, Palese P, Parkman PD, Saldarini RJ, Sisk JE, Tuomanen E, Weigler BJ, Westpheling J. Giving Full Measure to Countermeasures. Addressing problems in the DoD program to develop medical countermeasures against biological warfare agents. Institute of Medicine, National Research Council. The National Academies Press, Washington, DC, 2004.

Weigler BJ. Microbiological monitoring of rodent production: issues and options. Statistical issues. 55th American Association for Laboratory Animal Science Annual Meeting, Tampa, FL, Oct. 17-21, 2004.

Hankenson FC, Johnston NA, Weigler BJ, Di Giacomo RF. Zoonoses of occupational health importance in contemporary laboratory animal research. Comparative Medicine 2003;53:579-601.

Festing MFW, Weigler BJ. Experimental design and statistical analysis. In, J. Hau and G.L. Van Hoosier (eds). Handbook of Laboratory Animal Science, Vol. 1, Selection and Handling of Animal in Biomedical Research. CRC Press, Boca Raton, 2003.

Murphy FA, Roberts JA, Bayne KAL, Blanchard JL, Ferguson TJ, Flynn LJ, Geissert J, Hilliard JK, Kiley M, Peters CJ, and Weigler BJ. Occupational Health and Safety in the Care and Use of Non-Human Primates. Institute for Laboratory Animal Research, National Research Council. The National Academies Press, Washington, DC, 2003.

Weigler BJ, Spector MR, Vieira J, Sale GE, Storb RF. Systemic canine herpesvirus disease in adult dogs during immunosuppressive regimens for bone marrow transplant experiments. 54th American Association for Laboratory Animal Science Annual Meeting, Seattle, WA, Oct. 13-16, 2003.

Shiozaki D, Weigler BJ. Risk Assessment and Risk Management of Cyclosporine Exposure in Animal Technicians. 7th CDC National Biosafety Symposium. Atlanta, GA, Jan 27-30, 2002.

Weigler BJ. A primer in epidemiologic methodology. Comparative Medicine 2001;51:208-217.

Weigler BJ, Slattum MM. Multivariable regression analysis and other findings from the 1999 joint ASLAP/ACLAM economic survey of laboratory animal veterinarians. Contemporary Topics in Laboratory Animal Science 2001;40(5):9-13.

Weigler BJ. Risks of Working with Laboratory Animals – Nonhuman Primates. 6th National Biosafety Symposium. CDC and the Eagleson Institute. Atlanta, GA, Feb. 7-9, 2000.

Weigler BJ, Ponce RA. A quantitative risk model for laboratory-acquired Herpes B virus infection at a regional primate research facility. Infectious Disease Reviews 1999;1(3):220.

Nasisse MP, Glover TL, Moore CP, Weigler BJ. Detection of feline herpesvirus-1 DNA in corneas of cats with eosinophilic keratitis or corneal sequestration. American Journal of Veterinary Research 1998 59: 856-858.