Cardiovascular Biostatistics Training Program

The Department of Biostatistics runs a training program in Cardiovascular Biostatistics, funded by the National Heart, Lung, and Blood Institute

This program adds a focus on cardiovascular disease to the PhD program in Biostatistics. Biostatisticians at UW have been involved in research on the treatment and prevention of heart disease since the department was founded.

Cardiovascular Biostatistics Research at UW

Key clinical trials with leadership from UW biostatisticians include CASS (in the 1970s), which evaluated the effectiveness of heart bypass surgery, CAST (1980s), which showed that a popular class of drugs for heart rhythm disturbances was lethal, AVID (1990s), which demonstrated the benefits of implantable defibrillators, and the ongoing Women's Health Iniative studying the effects of hormone therapy, calcium supplements, and low fat diet.

UW biostatisticians also participate in many observational research projects in cardiovascular disease. The Cardiovascular Health Study is following a cohort of 5888 people aged 65-100 in 1989. The primary focus of CHS was on subclinical disease, but it has been a valuable resource for many types of research. The Multiethnic Study of Atherosclerosis is in its early stages, studying the build-up of calcium in plaque in the coronary arteries. Ancillary studies to MESA include a ten-year study of the impact of air pollution on heart disease. Other major efforts include genetic and genomic studies of heart disease to understand the mechanisms that lead to atherosclerosis, and pharmacogenomic research to find ways to help doctors and patients choose the most effective drugs on an individual basis.

The Training Program

The training program in cardiovascular biostatistics is based on the PhD degree. Prospective students must apply to the PhD program in the usual way. Training grants in cardiovascular biostatistics are made to approximately two students each year, either at admission or in later years.

The training program differs from the usual PhD program in biostatistics primarily in focusing the required study in biology on cardiovascular disease. Trainees still take the rigorous sequences of courses in statistical theory and methodology for which UW Biostatistics is known, but additional opportunities are available for collaborating on cardiovascular research projects.