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Jared Baeten, MD, PhD

  • Associate Professor, Departments of Global Health and Medicine
    Adjunct Associate Professor, Department of Epidemiology
  • University of Washington

Dr. Baeten is an associate professor in the Departments of Global Health and Medicine and an adjunct associate professor in the Department of Epidemiology at the University of Washington. His research focuses on epidemiologic and biologic risk factors for HIV-1 and other sexually transmitted diseases, and clinical trials of novel interventions for prevention of HIV-1 transmission. He co-chaired the Partners PrEP Study, a phase III, randomized clinical trial among ~4700 HIV-1 uninfected heterosexual men and women in Kenya and Uganda that demonstrated pre-exposure prophylaxis (PrEP) provided protection against HIV-1 acquisition. Linked projects included a large observational study of PrEP adherence and laboratory analyses of innate and adaptive immune responses related to PrEP use. Other current projects include a) a multinational phase III trial of dapivirine vaginal ring for HIV-1 prevention in women (MTN-020/ASPIRE, through the NIH Microbicides Trials Network, for which he serves as protocol chair), b) implementation studies of combination HIV-1 prevention in South Africa and Uganda, c) epidemiologic studies exploring use of hormonal contraception as a risk factor for HIV-1, and d) demonstration projects to deliver antiretroviral treatment and PrEP for HIV-1 prevention in African HIV-1 serodiscordant couples.


Selected Publications


Baeten JM, Donnel D, Ndase P, et al for the Partners PrEP Study Team. Antiretroviral prophylaxis for HIV prevention in heterosexual men and women. N Engl J Med. 2012; 367(5): 399-410.
PubMed Abstract


Donnell D, Baeten JM, Kiarie J, et al; Partners in Prevention HSV/HIV Transmission Study Team. Heterosexual HIV-1 transmission after initiation of antiretroviral therapy: a prospective cohort analysis. Lancet. 2010; 375(9731): 2092-8.
PubMed Abstract


Baeten JM, Kahle E, Lingappa JR, et al; Partners in Prevention HSV/HIV Transmission Study Team. Genital HIV-1 RNA predicts risk of heterosexual HIV-1 transmission. Sci Transl Med. 2011; 3(77): 77ra29.
PubMed Abstract


Mugwanya K, Donnell D, Celum C, Thomas KK, Ndase P, Mugo N, Katabira E, Ngure K, Baeten JM, for the Partners PrEP Study Team. Sexual behavior of heterosexual men and women receiving antiretroviral pre-exposure prophylaxis for HIV prevention. Lancet Infectious Diseases 2013; 13:1021-8..
PubMed Abstract


Hallett TB, Baeten JM, Heffron R, et al. Optimal uses of antiretrovirals for prevention in HIV-1 serodiscordant heterosexual couples in South Africa: a modelling study. PLoS Med. 2011; 8(11): e1001123.
PubMed Abstract


Heffron R, Donnell D, Rees H, Celum C, Mugo N, Were E, de Bruyn G, Nakku-Joloba E, Ngure K, Kiarie J, Coombs RW, Baeten JM for the Partners in Prevention HSV/HIV Transmission Study Team. Hormonal contraceptive use and risk of HIV-1 transmission: a prospective cohort analysis. Lancet Infect Dis. 2012; 12(1): 19-26.
PubMed Abstract