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Directory >> Ann Collier, MD


Contact Information

Ann Collier, MD

  • Professor of Medicine, Division of Allergy and Infectious Diseases
  • University of Washington
  • Director, UW AIDS Clinical Trials Unit
  • Associate Director, Center for AIDS Research
    University of Washington and Fred Hutch

Dr. Collier's ongoing clinical research interests include antiretroviral therapy, HIV reservoirs and cure, natural and treated history of primary HIV infection, and the effects of antiretroviral therapy on neurological aspects of HIV infection.

Her ongoing studies include collaborative projects to investigate long-acting antiretroviral drugs and regimens, third line antiretroviral treatment in resource-limited settings, observational studies to evaluate factors associated with HIV reservoir size and long-term outcomes in treated HIV infection, determinants of successful screening for participation in AIDS Clinical Trials Group protocols, and a variety of pilot studies of antiviral and anti-inflammatory agents.

Dr. Collier's ongoing collaborations include local projects with Drs. Joanne Stekler, James Mullins, Christina Marra, Sarah Holte, and Robert Coombs as well as collaborations with other U.S.-based and international colleagues.

Sample projects that trainees might become involved with include third line antiretroviral treatment in resource-limited settings, transition of care from research to clinical care settings, barriers for the conduct of clinical trials in resource-limited settings, determinants of HIV reservoir size, and impact of treatment of acute HIV infection on latently infected CD4 T cells.

Selected Publications

Maenza J, Tapia K, Holte S, Stekler JD, Stevens CE, Mullins JI, Collier AC. How often does treatment of primary HIV lead to post-treatment control? Antivir Ther. 2015 Apr 23. doi: 10.3851/IMP2963. [Epub ahead of print]

Gross R, Zheng L, La Rosa A, Sun X, Rosenkranz SL, Cardoso SW, Ssali F, Camp R, Godfrey C, Cohn SE, Robbins GK, Chisada A, Wallis CL, Reynolds NR, Lu D, Safren SA, Hosey L, Severe P, Collier AC. Partner-focused adherence intervention for second-line antiretroviral therapy: A multinational randomized trial (ACTG A5234). Lancet HIV. 2015 Jan 1;2(1):e12-e19. PMCID: PMC4313760
PubMed Abstract

Smith KY, Tierney C, Mollan K, Venuto CS, Budhathoki C, Ma Q, Morse GD, Sax P, Katzenstein D, Godfrey C, Fischl M, Daar ES, Collier AC and the ACTG 5202 Team. Outcomes by sex following treatment initiation with atazanavir plus ritonavir or efavirenz with abacavir/lamivudine or tenofovir/emtricitabine. Clin Infect Dis 2014;58(4):555-63]. PMID:24253247
PubMed Abstract

Zheng L, Taiwo B, Gandhi RT, Hunt PW, Collier AC, Flexner C, Bosch RJ. Factors associated with CD8+ T-cell activation in HIV-1-infected patients on long-term antiretroviral therapy. JAIDS 2014 Oct 1;67(2):153-60. PMCID: PMC4167746
PubMed Abstract

Marra CM, Deutsch R, Collier AC, Morgello S, Letendre S, Clifford D, Gelman B, McArthur J, McCutchan JA, Simpson DM, Duarte NA, Heaton RK and Grant. Neurocognitive impairment in HIV-infected individuals with previous syphilis. Intern J STDs AIDS 2013 May;24(5):351-5. PMID:23970701
PubMed Abstract

Stekler JD, McKernan J, Milne R, Tapia KA, Mykhalchenko K, Holte S, Maenza J, Stevens CE, Buskin SE, Mullins JI, Frenkel LM, Collier AC. Lack of resistance to integrase inhibitors among antiretroviral-naïve subjects with primary HIV-1 infection, 2007-2013. Antiviral Therapy 2015; 20(1):77-80. PMCID: PMC4312242
PubMed Abstract

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