UW Medicine Division of Allergy and Infectious Diseases
Directory >> Ann Collier, MD

Faculty

Ann Collier, MD

  • Professor of Medicine
  • University of Washington
  • Director, UW Adult AIDS Clinical Trials Unit
  • Associate Director UW/FHCRC Center for AIDS Research

Ongoing clinical research projects include studies of antiviral treatments for HIV and its associated complications, natural and treated history of primary HIV infection, and the effects of antiretroviral therapy on neurological aspects of HIV infection.

Ongoing studies include collaborative projects to investigate the pathogenesis of HIV infection, observational studies to characterize the long-term outcomes of treated HIV infection, and a variety of treatment studies.

Ongoing collaborations include projects with Drs. Joanne Stekler, James Mullins, Christina Marra, Sarah Holte, Jashvant Unadkat, Robert Coombs, and Mari Kitahara, as well as with international colleagues.

Selected Publications

Stekler JD, Ellis GM, Carlsson J, Eilers B, Holte S, Maenza J, Stevens CE, Collier AC, Frenkel LM. Prevalence and impact of minority variant drug resistance mutations in primary HIV-1. PLoS One 2011;6(12):e28952.
[The following link will open in a new window. PubMed Abstract ]

Daar ES, Tierney C, Fischl MA, Sax PE , Mollan K, Budhathoki C, Godfrey C , Jahed N, Myers L, Katzenstein D, Farajallah A, Rooney JF., Pappa KA, Woodward WC, Patterson K, Bolivar H, Benson CA, Collier AC for the AIDS Clinical Trials Group Study A5202 Team. Atazanavir plus ritonavir or efavirenz as part of a three drug regimen for initial treatment of HIV-1:  A randomized trial. Ann Intern Med 2011;154(7):445-6.
[ The following link will open in a new window. PubMed Abstract ]

Ellis RJ, Badiee J, Vaida F, Letendre S, Heaton RK, Clifford D, Collier AC, Gelman B, McArthur J, Morgello S, McCutchan JA, Grant I; CHARTER Group. CD4 nadir is a predictor of HIV neurocognitive impairment in the era of combination antiretroviral therapy. AIDS 2011;25(14):1747-51.
[ The following link will open in a new window. PubMed Abstract ]

Smurzynski M, Wu D, Letendre S, Robertson K, Bosch RJ, Clifford DB, Evans S, Collier AC, Taylor M, Ellis R. Effects of central nervous system antiretroviral penetration on cognitive functioning in the ALLRT cohort. AIDS 2011 Jan 28;25(3):357-65.
[The following link will open in a new window. PubMed Abstract ]

Kirby BJ, Collier AC, Kharasch ED, Dixit V, Desai P, Whittington D, Thummel KE, Unadkat JD. Complex drug interactions of HIV protease inhibitors 2: In vivo induction and in vitro to in vivo correlation of induction of cytochrome P450 1A2, 2B6 and 2C9 by ritonavir or nelfinavir. Drug Metab Dispos 2011 Sep 19 2011 Dec;39(12):2329-37.
[The following link will open in a new window. PubMed Abstract ]

Chun TW, Justement JS, Murray D, Hallahan CW, Maenza J, Collier AC, Sheth PM, Kaul R, Ostowski M, Moir S, Kovacs C, Fauci AS. Rebound of plasma viremia following cessation of antiretroviral therapy despite profoundly low levels of HIV reservoir: Implications for eradication. AIDS 2010 Nov 27;24(18):2803-8.
[The following link will open in a new window. PubMed Abstract ]

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