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Directory >> Gregory J. Crowther, PhD

Faculty

Contact Information

Gregory J. Crowther, PhD

  • Acting Assistant Professor, Allergy and Infectious Diseases
  • University of Washington

Dr. Crowther's current work focuses on target-based drug development with an emphasis on neglected diseases such as malaria. Specific interests include bioinformatic prioritization of possible drug targets and biochemical and biophysical screening assays. Graduate and postdoctoral training concerned regulation of metabolic pathways in methylotrophic bacteria and exercising human muscles. Pedagogical interests include the incorporation of primary literature and educational songs into curricula.


Selected Publications


Crowther G. Using science songs to enhance learning: An interdisciplinary approach. CBE Life Sci Educ. 2012; 11(1): 26-30.
PubMed Abstract


Crowther GJ, Quadri SA, Shannon-Alferes BJ, Van Voorhis WC, Rosen H. A mechanism-based whole-cell screening assay to identify inhibitors of protein export in Escherichia coli by the Sec pathway. J Biomol Screen. 2012; 17(4): 535-41.
PubMed Abstract


Crowther GJ, Napuli AJ, Gilligan JH, et al. Identification of inhibitors for putative malaria drug targets among novel antimalarial compounds. Mol Biochem Parasitol. 2011; 175(1): 21-9.
PubMed Abstract


Crowther GJ, Shanmugam D, Carmona SJ, et al. Identification of attractive drug targets in neglected-disease pathogens using an in silico approach. PLoS Negl Trop Dis. 2010;4(8):e804.
PubMed Abstract


Guiguemde WA, Shelat AA, Bouck D, Duffy S, Crowther GJ, Davis PH, et al. Chemical genetics of Plasmodium falciparum. Nature. 2010; 465(7296), 311-5.
PubMed Abstract


Crowther GJ, Napuli AJ, Thomas AP, et al. Buffer optimization of thermal melt assays of Plasmodium proteins for detection of small-molecule ligands. J Biomol Screen. 2009; 14(6), 700-7.
PubMed Abstract


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