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Directory >> Grace John-Stewart, MD, MPH, PhD

Faculty

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Grace John-Stewart, MD, MPH, PhD

  • Professor, Division of Allergy and Infectious Diseases, Department of Medicine and
    Departments of Epidemiology, Global Health, and Pediatrics
  • University of Washington

Dr. John-Stewart's major research interest is in studies of HIV-1 infection in Africa. She directs several large cohort studies aimed at defining mechanisms of HIV-1 transmission between sexual partners and from mothers to infants in Kenya. Particular research interests include prevention of mother-to-child HIV-1 transmission (PMTCT) clinical trials, implementation science and evaluation studies, pediatric HIV-1 studies, HIV-1 treatment programs and evaluation.   Her group also focuses on maternal-child epidemiologic studies in the context of infectious diseases including studies of the mechanism of breastfeeding protective effects, child growth and neurocognitive outcomes, preterm birth, viral infections with EBV, CMV, and TB.  She collaborates with Drs. Farquhar, Richardson, Overbaugh, Chung, McClelland, Slyker  Benki-Nugent, and Walson.

Potential research projects, that could offer opportunites to fellows, could focus on PMTCT program evaluation and implementation, cofactors for preterm birth, STIs during pregnancy and their impact on infant outcomes, infant growth, or pediatric HIV.


Selected Publications (of 160+)

Nduati R, John G, Mbori-Ngacha D, Richardson B, Overbaugh J, Mwatha A, et al. Effect of breastfeeding and formula feeding on transmission of HIV-1: a randomized clinical trial. JAMA. 2000; 283(9):1167-74.
PubMed Abstract


Jonnalagadda S, Lohman-Payne B, Brown E, Wamawa D, Obimbo E, Farquhar C, Otieno P, Mbori-Ngacha D, John-Stewart G. Latent tuberculosis detection by interferon ? release assay during pregnancy predicts active tuberculosis and mortality in human immunodeficiency virus type 1-infected women and their children. J Infect Dis. 2010; 202(12): 1826-35.
PubMed Abstract


Walson JL, Singa BO, Sangaré L, Naulikha J, Piper B, Richardson BA, Otieno PA, Mbogo LW, Berkley J, John-Stewart G. Empiric deworming to delay HIV disease progression in adults with HIV who are ineligible for initiation of antiretroviral treatment (the HEAT study): a multi-site, randomised trial. Lancet Infect Dis. 2012;12(12): 925-32.
PubMed Abstract


Slyker J, Casper C, Tapia K, Richardson BA, Bunts L, Huang ML, Maleche-Obimbo E, Nduati R, John-Stewart G. Clinical and virologic manifestations of primary Epstein-Barr (EBV) infection in Kenyan infants born to HIV-infected women. J Infect Dis. 2013; 207(12): 1798-806.
PubMed Abstract

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