UW Medicine Division of Allergy and Infectious Diseases
Directory >> Grace John-Stewart, MD, MPH, PhD

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Grace John-Stewart, MD, MPH, PhD

  • Professor of Medicine, Epidemiology, Global Health, and Pediatrics
  • University of Washington

Dr. John-Stewart's major research interest is the epidemiology and transmission of HIV-1 infection in Africa. She directs several large cohort studies aimed at defining mechanisms of HIV transmission between sexual partners and from mother to infants in Nairobi, Kenya. In addition, her group is conducting studies to evaluate HIV-1 progression, with studies targeted to evaluate the role of lactation, contraception, and co-infections on HIV-1 pathogenesis. Particular research interests include determinants of mother-to-child transmission of HIV-1, breast milk transmission of HIV-1, correlates of immune protection from HIV-1, HIV-1 treatment and resistance following HAART in resource-poor settings, and pediatric HIV-1 pathogenesis.

Molecular epidemiology studies and clinical trials are the focus of her research group. She collaborates with Drs. Farquhar, Richardson, Overbaugh, Chung, McClelland and Walson.


Selected Publications (of 140)


Nduati, R., John, G., Mbori-Ngacha, D., Richardson, B., Overbaugh, J., Mwatha, A., Ndinya-Achola, J., Bwayo, J., Onyango, F.E., Hughes, J. & Kreiss, J. (2000). Effect of breastfeeding and formula feeding on transmission of HIV-1: a randomized clinical trial. JAMA, 283, 1167-74.
[The following link will open in a new window. PubMed Abstract ]


Brown, E., Otieno, P., Mbori-Ngacha, D., Farquhar, C., Obimbo, E., Nduati, R., Overbaugh, J., & John-Stewart, G. (2009). Comparison of CD4 cell count, viral load, and other markers for the prediction of mortality among HIV-1-infected Kenyan pregnant women. J Infect Dis, 199(9), 1292–1300.
[ The following link will open in a new window. PubMed Abstract ]


Slyker, J., Lohman-Payne, B., Rowland-Jones, S., Otieno, P., Maleche-Obimbo, E., Richardson, B., Dong, T., Mbori-Ngacha, D., Emery, V., & John-Stewart, G. (2009). The detection of cytomegalovirus DNA in maternal plasma is associated with mortality in HIV-1 infected women and their infants. AIDS, 23(1), 117-24.
[ The following link will open in a new window. PubMed Abstract ]


Walson, J.L., Otieno, P.A., Mbuchi, M., Richardson, B., Lohman-Payne, B., Macharia, S.W., Overbaugh, J., Berkley, J., Sanders, E., Chung, M., & John-Stewart, G.C. (2008). Albendazole treatment of HIV-1 and helminth co-infection: a randomized, double-blind, placebo-controlled trial. AIDS, 22(13), 1601-1609.
[The following link will open in a new window. PubMed Abstract ]

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