Dr. Pergam's research focuses on the prevention of infections in patients with cancer, transplant recipients and other immunocompromised populations. He focuses on the immunogenetics of innate responses to Cytomegalovirus in hematopoietic cell transplant recipients. Current studies include the evaluation of natural killer associated KIR and CMV outcomes post-transplant. He has research programs that are currently evaluating the use of viral kinetics and advanced diagnostics to improve diagnosis of CMV complications. Dr. Pergam also has an interest in the epidemiology and prevention of viral infections in cord blood transplant recipients and other high-risk HCT populations.
As the Associate Director of Infection Control, Dr Pergam is actively involved in the development of new infection control strategies and educational programs. He has active research projects that aim to better understand the epidemiology of nosocomial bacterial infections and respiratory viruses in cancer patients.
Pergam SA, Xie H, Sandhu R, et al. Efficiency and risk factors for CMV transmission in seronegative hematopoietic stem cell recipients. Biol Blood Marrow Transplant. 2012;18(9):1391-400.
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Milano F, Pergam SA, Xie H, et al. Intensive strategy to prevent CMV disease in seropositive umbilical cord blood transplant recipients. Blood. 2011; 118(20), 5689-96. PMID: 21937692. PMCID: PMC3217367.
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Gooley TA, Chien JW, Pergam SA, et al. Reduced mortality after allogeneic hematopoietic-cell transplantation. N Engl J Med. 2010; 363(22): 2091-101. PMID: 21105791. PMCID: PMC3017343.
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Pergam SA, Forsberg CW, Boeckh MJ, et al. (2011). Herpes zoster incidence in a multicenter cohort of solid organ transplant recipients. Transpl Infect Dis. 2011; 13(1); 15-23. PMID: 20636480. PMCID: PMC2976841.
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Travi G, Pergam SA, Xie H, et al. The effect of imatinib on cytomegalovirus reactivation in hematopoietic cell transplantation. Clin Infect Dis. 2009; 49(11); e120-3. PMID:19886798.
PMCID: PMC2779734.
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