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Steven Self, PhD

  • Professor, Department of Biostatistics
  • University of Washington

  • Member, Fred Hutchinson Cancer Research Center

Dr. Self is currently Full Member and Head of the Program in Biostatistics and Biomathematics and Co-Director (with Drs. Corey and McElrath) of the Vaccine and Infectious Disease Institute (VIDI) at the Hutchinson Cancer Research Center. Dr. Self's research program over the past several years has been directed at the overarching goal of identification and evaluation of a broadly effective HIV vaccine. This work is organized in the broad areas of Phase I/II Vaccine trial designs, Vaccine trial endpoints and Immunologic correlates of protection.

Dr. Self has a long-standing interest in the analysis of genomics data and has maintained this interest largely by advising graduate students in their dissertation research in this area.

Selected Publications

Abu-Raddad LJ, Boily MC, Self S, Longini IM, Jr. Analytic insights into the population level impact of imperfect prophylactic HIV vaccines. J Acquir Immune Defic Syndr. 2007; 45: 454-67.
PubMed Abstract

Brander C, Self S, Korber B. Capturing viral diversity for in-vitro test reagents and HIV vaccine immunogen design. Curr Opin HIV AIDS. 2007; 2: 183-8. doi: 10.1097/COH.0b013e3280f3bfe2.
PubMed Abstract

Qin L, Gilbert PB, Corey L, McElrath MJ, Self SG. A framework for assessing immunological correlates of protection in vaccine trials. J Infect Dis. 2007; 196:1304-12.
PubMed Abstract

Moodie Z, Rossini AJ, Hudgens MG, Gilbert PB, Self SG, Russell ND. Statistical evaluation of HIV vaccines in early clinical trials. Contemp Clin Trials 2006; 27: 147-60.
PubMed Abstract

Gilbert PB, Qin L, Self SG. Evaluating a surrogate endpoint at three levels, with application to vaccine development. Stat Med. 2008; 27: 4758-78.
PubMed Abstract

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