Dr. Stekler's research is focused in two primary areas:
With the Public Health - Seattle & King County HIV/AIDS Program, Dr. Stekler is working to expand routine HIV antibody testing and access to pooled HIV nucleic acid amplification testing to diagnose acute HIV infection. She leads several studies investigating novel methods to diagnose acute and early HIV infection; comparisons of rapid HIV tests; and home, self-testing for HIV infection. Dr. Stekler also works at the University of Washington Primary Infection Clinic within the clinical core of the Seattle Primary Infection Program (SeaPIP), a collaboration of local and national virologists, immunologists, and clinicians. Since 1992, the Primary Infection Clinic has enrolled and followed over 300 persons with acute and early HIV infection. Dr. Stekler's interests include interdisciplinary research to understand factors associated with HIV transmission, consequences of transmitted drug resistance, viral dynamics following HIV acquisition, and clinical outcomes of antiretroviral therapy during primary HIV infection.
Stekler JD, Swenson PD, Coombs RW, Dragavon J, Thomas KK, Brennan CA, Devare SG, Wood RW, Golden MR. HIV Testing in a High Incidence Population: Is Antibody Testing Alone Good Enough? Clinical Infectious Diseases 2009 Aug 1;49(3):444-53.
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Stekler J, Sycks BJ, Holte S, Maenza J, Stevens CE, Dragavon J, Collier AC, Coombs RW. HIV dynamics in seminal plasma during primary HIV infection. AIDS Research and Human Retroviruses 2008 Oct; 24(10): 1269-74.
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Stekler J, Maenza J, Stevens CE, Swenson PD, Coombs RW, Wood RW, Campbell MS, Nickle DC, Collier AC, Golden MR. Screening for acute HIV infection: lessons learned. Clin Infect Dis 2007 Feb 1; 44(3): 459-61.
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Stekler J, Maenza J, Stevens C, Holte S, Malhotra U, McElrath MJ, Corey L, Collier AC. Abacavir hypersensitivity reaction in primary HIV infection. AIDS 2006, 20: 1269-1274.
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Stekler J, Collier AC, Holmes KK, Golden MR. Primary HIV infection education: knowledge and attitudes of HIV-negative men who have sex with men (MSM) attending a public health STD clinic. J Acq Immun Def Syndr 2006 May; 42(1): 123-6.
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Branson BM, Stekler JD. Detection of Acute HIV Infection: We Can't Close the Window. J Infect Dis. 2012 Feb;205(4):521-4. Epub 2011 Dec 29.
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Stekler JD, Ellis GM, Carlsson J, Eilers B, Holte S, Maenza J, Stevens CE, Collier AC, Frenkel LM. Prevalence and impact of minority variant drug resistance mutations in primary HIV-1 infection. PLoS One. 2011;6(12):e28952. Epub 2011 Dec 16.
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Dombrowski JC, Kent JB, Buskin SE, Stekler JD, Golden MR. Population-based metrics for the timing of HIV diagnosis, engagement in HIV care, and virologic suppression. AIDS. 2012 Jan 2;26(1):77-86.
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Coffin PO, Stevens AM, Scott JD, Stekler JD, Golden MR. Patient acceptance of universal screening for hepatitis C virus infection. BMC Infect Dis. 2011 Jun 6;11:160. doi: 10.1186/1471-2334-11-160.
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