John e. Olerud, MD

Professor Emeritus, Division of Dermatology

Contact Information

University of Washington
Box 354697
Seattle, WA 98195-6524

Clinic Appointments:206-598-4067
Clinic Fax: 206-598-2267


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Education and Training

M.D., University of Washington School of Medicine, 1971
Residency in Internal Medicine, University of Washington, 1975
Residency in Dermatology, University of Washington, 1977

Research Interests

Abnormal wound healing in patients with diabetes mellitus; cutaneous T-cell lymphoma; and biomaterials/skin interface.

Clinical Research Interests

Cutaneous lymphoma, skin manifestations of diabetes and internal diseases, leg ulcers and connective tissue diseases.

Representative Publications

Olerud JE. Models for Wound Healing and Healing into Percutaneous Devices. J Biomat Sci, Polymer Edn Vol. 19, No. 8, pp. 1007-20, 2008. PMID 18644227

Fukano Y, Usui ML, Underwood RA, Isenhath S, Marshall AJ, Hauch KD, Ratner BD, Olerud JE, Fleckman P. Epidermal and dermal integration into sphere-templated porous poly(2-hydroxyethyl methacrylate) implants in mice. J Biomed Mater Res A. Sep 15;94(4):1172-86, 2010. PMID: 20694984

Zhao G, Hochwalt PC, Usui ML, Underwood RA, Singh PK, James GA, Stewart PS, Fleckman P, Olerud JE. Delayed wound healing in diabetic (db/db) mice with Pseudomonas aeruginosa biofilm challenge: a model for the study of chronic wounds, Wound Repair Regen. 2010 18(5):467-77, 2010. PMID: 20731798

Kalus AA, Chien AC, Olerud JE. Chapter 152: Diabetes mellitus and other endocrine diseases, in Fitzpatrick?s Dermatology in General Medicine 8th edition, in press. Eds. Wolff, Goldsmith, Katz, et al, McGraw-Hill, In Press, 2010.

Secor PR, James GA, Fleckman PH, Olerud JE, McInnerney K, Stewart PS.  Staphylococcus aureus biofilm and planktonic cultures differentially impact gene Expression, MAPK phosphorylation, and cytokine production in human keratinocytes. BMC Microbiol. Jun;11:143, 2011.  PMID: 21693040, PMCID: PMC3146417

Fleckman P, Usui ML, Zhao GA, Underwood RA, Maginness M, Marshall A, Glaister C, Ratner R, Olerud JE.  Cutaneous and inflammatory response to long-term percutaneous implants of sphere-templated porous/solid poly(HEMA) and silicone in Mice.  J Biomed Mat Res A. Feb 23, 2012. [Epub ahead of print].  PMID: 22359383

Kirker KR, James GA, Fleckman PH, Olerud JE, Stewart PS.  Differential Effects of Planktonic and Biofilm MRSA on Human Fibroblasts.  Wound Repair Regen. Mar-Apr;20(2):253-61, 2012. Epub Feb 14, 2012.  PMID: 22332802, PMCID: PMC3292663

  1. Secor PR, Jennings LK, James GA, Kirker KR, Pulcini ED, McInnerney K, Gerlach R, Livinghouse, Hilmer JK, Bothner B, Fleckman P, Olerud JE, Stewart PS.  Phevalin (aureusimine B) Production by Staphylococcus aureus Biofilm and Impacts on Human Keratinocyte Gene Expression. PLoS One. 7(7):e40973, 2012.  PMID: 22808288, PMCID: PMC 3396627
  2. Zhao G, Usui ML, Underwood RA, Singh PK, James GA, Stewart PS, Fleckman P, Olerud JE.  Time course study of delayed wound healing in a biofilm-challenged diabetic mouse model. Wound Repair Regen. 20(3):342-52, 2012.  PMID: 22564229, PMCID: PMC 3349451
  3. Usui ML, Underwood RA, Fleckman P, Olerud JE.  Parakeratotic corneocytes play a unique role in human skin wound healing. J Invest Dermatol. 2013 Mar;133(3):856-8. doi: 10.1038/jid.2012.352. Epub Sep 27, 2012. PMID: 23014344 PMCID: PMC3532577
  4. Zhao G, Chamberlain MC, Khot SP, Shustov A, Olerud JE, Shinohara MM.  Central Nervous System Involvement in Cutaneous T-cell Lymphoma: 2 Illustrative Cases and a Review of Current Literature. Clin Lymphoma Myeloma Leuk. Oct 1, 2013. pii: S2152-2650(13)00437-0. doi: 10.1016/j.clml.2013.09.016. PMID: 24262331
  5. Choi W-T, Stetsenko GY, Zhang J, Olerud JE, Argenyi ZB, George E.  Cutaneous angiosarcoma clinically presenting as progressive solid facial edema in a 43-your-old male. Dermatol Online J. 19(11):20409, Nov 15, 2013. PMID: 24314784
  6. Zhao G, Usui ML, Lippman S, James GA, Stewart PS, Fleckman P, Olerud JE. Biofilms and Inflammation in Chronic Wounds, 2013.

    For a complete listing of all publications, please email

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