 Professor, Division of Dermatology
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CONTACT INFORMATION Philip Fleckman, M.D. |
EDUCATION AND TRAINING M.D., Washington University School of Medicine, 1973 Internship in Medicine at Barnes Hospital, 1973-74 Postdoctoral fellowship in the USPHS, NIMH, NIH, Bethesda, MD, Residency in Dermatology, Yale University School of Medicine, 1978-80 RESEARCH AND CLINICAL INTERESTS Research: Developmental biology of the distal digit. Healing skin around percutaneous devices. The pathophysiology of the ichthyoses. Most of these studies focus on in vitro models of epidermis. Clinical: General dermatology with special interest in individuals with inherited disorders of keratinization, with nail disorders, and with blistering skin disorders. Dr. Fleckman is the Principal Investigator of the National Registry for Ichthyosis and Related Disorders, an NIH-sponsored research registry for individuals with disorders of keratinization, and is the editor emeritus of the Dermatology Online Journal. REPRESENTATIVE PUBLICATIONS Mecklenburg L, Paus R, Halata Z, Bechtold LS, Fleckman P, Sundberg JP: FOXN1 is Critical for Onychocyte Terminal Differentiation Nude (Foxn1nu) Mice. J Invest Dermatol 123:1001-11, 2004. Allan CH, Fleckman P, Fernandes RJ, Hager B, James J, Wisecarver Z, Satterstrom FK, Norman A, Pirrone A, Rubin BP, Zhang M, Ramay HR, Clark JM. Human fetal digit response to tip amputation in vitro. Wound Repair and Regeneration 14:484-491, 2006. Fukano Y, Knowles NG, Usui ML, Underwood RA, Hauch KD, Marshall AJ, Ratner BD, Giachelli C, Carter WG, Fleckman P, Olerud JE: Characterization of an in vitro model for evaluating the interface between skin and percutaneous biomaterials. Wound Repair Regen 14:484-491, 2006. Smith FJD, Irvine AD, Terron-Kwiatkowski A, Sandilands A, Campbell LE, Zhao Y, Liao H, Evans AT, Goudie DR, Lewis-Jones S, Arseculeratne G, Munro CS, Sergeant A, O’Regan G, Bale SJ, Compton JG, DiGiovanna JJ, Presland RB, Fleckman P, McLean WHI: Loss-of-function mutations in the filaggrin gene cause ichthyosis vulgaris. Nat Genet 38:337-342, 2006. Isenhath SN, Fukano Y, Usui ML, Underwood RA, Irvin CA, Marshall AJ, Hauch KD, Ratner BD, Fleckman P, Olerud JE: A mouse model to evaluate the interface between skin and a percutaneous device. In press, J Biomed Mater Res A, 2007. ADDITIONAL REPRESENTATIVE PUBLICATIONS Dermatology Home | Dermatology Table of Contents | DOM Home | UW Home
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