research

Dermatology Research Projects and Centers

Paul Nghiem Laboratory

The Nghiem Laboratory, headed by Dr. Paul Nghiem, studies cell cycle control in normal and cancer cells with an ultimate goal of discovering new approaches to prevent and treat cancer. The focus is a protein kinase called ATR that is required for the replication checkpoint -- the means by which a cell ensures it does not undergo mitosis before completely replicating its DNA. Our prior work has demonstrated that loss of tumor suppressors such as p53 markedly sensitizes cells to death by inhibition of ATR function. For more information about this laboratory and the research being produced, please visit the website.

National Registry for Ichthyosis and Related Disorders

Headed by principal investigator Dr. Philip Fleckman, the National Registry for Ichthyosis and Related Disorders was created with the support of the National Institutes for Health to encourage research into the diagnosis and treatment of the ichthyoses and related disorders. We have approached this goal by having people that are affected by these conditions enroll in the Registry as well as by sharing information about ongoing research projects with those who ask to be notified.

Persons with the following diagnoses are enrolled:

  • Inherited Ichthyosis
  • Erythrokeratodermas
  • Darier disease
  • Hailey-Hailey disease
  • Palmar-Plantar Keratodermas
  • Pachyonychia Congenita
  • Extensive Epidermal Nevi

For more information, please visit the Registry website.

 

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