Christiane Hampe

Research Associate Professor

South Lake Union



Research Interest: Etiology, Pathogenesis and Treatment of Type 1 Diabetes

DRC Publications

Chefdeville, A; Honnorat, J; Hampe, CS; Desestret, V ; Neuronal central nervous system syndromes probably mediated by autoantibodies Eur J Neurosci 43 12: 1535-52; 2016 PMC4914447

Bansal, N; Hampe, CS; Rodriguez, L; O'Brian Smith, E; Kushner, J; Balasubramanyam, A; Redondo, MJ ; DPD epitope-specific glutamic acid decarboxylase (GAD)65 autoantibodies in children with Type 1 diabetes Diabet Med 2016 PMC4958605

Rolandsson, O; Hampe, CS; Wennberg, P; Radtke, J; Langenberg, C; Wareham, N; EPIC-InterAct Study Group ; Prevalence and regional distribution of autoantibodies against GAD65Ab in a European population without diabetes: The EPIC-InterAct Study Diabetes Care 38 8: e114-5; 2015 PMC4512134

Yarlagadda, A; Acharya, G; Kasaraneni, J; Hampe, CS; Clayton, AH ; Placental Barrier and Autism Spectrum Disorders: The Role of Prolactin and Dopamine on the Developing Fetal Brain Innov Clin Neurosci 12 9-10: 14-7; 2015 PMC4655894

Gaba, R; Gambhire, D; Uy, N; Gonzalez, EV; Iyer, D; Hampe, CS; Ram, N; Balasubramanyam, A ; Factors associated with early relapse to insulin dependence in unprovoked A-beta+ ketosis-prone diabetes J Diabetes Complications 29 7: 918-22; 2015 PMC4540630

Ganelin-Cohen, E; Modan-Moses, D; Hemi, R; Kanety, H; Ben-Zeev, B; Hampe, CS ; Epilepsy and behavioral changes, type 1 diabetes mellitus and a high titer of glutamic acid decarboxylase antibodies Pediatr Diabetes 2015 PMC4927419

Gu Urban, GJ; Friedman, M; Ren, P; Torn, C; Fex, M; Hampe, CS; Lernmark, A; Landegren, U; Kamali-Moghaddam, M ; ... Kamali-Moghaddam, M Elevated Serum GAD65 and GAD65-GADA Immune Complexes in Stiff Person Syndrome Sci Rep 5 11196; 2015 PMC4468815

Manto, M; Honnorat, J; Hampe, CS; Guerra-Narbona, R; Lopez-Ramos, JC; Delgado-Garcia, JM; Saitow, F; Suzuki, H; Yanagawa, Y; ... Mitoma, H Disease-specific monoclonal antibodies targeting glutamate decarboxylase impair GABAergic neurotransmission and affect motor learning and behavioral functions Front Behav Neurosci 9 78; 2015 PMC4375997

Costa, OR; Stange, G; Verhaeghen, K; Brackeva, B; Nonneman, E; Hampe, CS; Ling, Z; Pipeleers, D; Gorus, FK; ... Martens, GA Development of an Enhanced Sensitivity Bead-Based Immunoassay for Real-Time In Vivo Detection of Pancreatic beta-Cell Death Endocrinology 156 12: 4755-60; 2015

Redondo, MJ; Rodriguez, LM; Haymond, MW; Hampe, CS; Smith, EO; Balasubramanyam, A; Devaraj, S ; Serum adiposity-induced biomarkers in obese and lean children with recently diagnosed autoimmune type 1 diabetes Pediatr Diabetes 15 8: 543-9; 2014 PMC4423898

Oak, S; Gaur, LK; Radtke, J; Patel, R; Iyer, D; Ram, N; Gaba, R; Balasubramanyam, A; Hampe, CS ; ... Hampe, CS Masked and overt autoantibodies specific to the DPD epitope of 65-kDa glutamate decarboxylase (GAD65-DPD) are associated with preserved beta-cell functional reserve in ketosis-prone diabetes J Clin Endocrinol Metab 99 6: E1040-4; 2014 PMC4037721

Vega-Flores, G; Rubio, SE; Jurado-Parras, MT; Gomez-Climent, MA; Hampe, CS; Manto, M; Soriano, E; Pascual, M; Gruart, A; ... Delgado-Garcia, JM The GABAergic septohippocampal pathway is directly involved in internal processes related to operant reward learning Cereb Cortex 24 8: 2093-107; 2014 PMC4441070

Rountree, AM; Neal, AS; Lisowski, M; Rizzo, N; Radtke, J; White, S; Luciani, DS; Kim, F; Hampe, CS; ... Sweet, IR Control of insulin secretion by cytochrome C and calcium signaling in islets with impaired metabolism J Biol Chem 289 27: 19110-9; 2014 PMC4081948

Redondo, MJ; Muniz, J; Rodriguez, LM; Iyer, D; Vaziri-Sani, F; Haymond, MW; Hampe, CS; Metzker, ML; Grant, SF; ... Balasubramanyam, A Association of TCF7L2 variation with single islet autoantibody expression in children with type 1 diabetes BMJ Open Diabetes Res Care 2 1: e000008; 2014 PMC4212574

Shulman, LM; Hampe, CS; Ben-Haroush, A; Perepliotchikov, Y; Vaziri-Sani, F; Israel, S; Miller, K; Bin, H; Kaplan, B; ... Laron, Z Antibodies to islet cell autoantigens, rotaviruses and/or enteroviruses in cord blood and healthy mothers in relation to the 2010-2011 winter viral seasons in Israel: a pilot study Diabet Med 31 6: 681-5; 2014 PMC4061376

Hampe, CS; Petrosini, L; De Bartolo, P; Caporali, P; Cutuli, D; Laricchiuta, D; Foti, F; Radtke, JR; Vidova, V; ... Manto, M Monoclonal antibodies to 65kDa glutamate decarboxylase induce epitope specific effects on motor and cognitive functions in rats Orphanet J Rare Dis 8 82; 2013 PMC3680042

Brooks-Worrell, BM; Iyer, D; Coraza, I; Hampe, CS; Nalini, R; Ozer, K; Narla, R; Palmer, JP; Balasubramanyam, A ; ... Balasubramanyam, A Islet-specific T-cell responses and proinflammatory monocytes define subtypes of autoantibody-negative ketosis-prone diabetes Diabetes Care 36 12: 4098-103; 2013 PMC3836121

Hampe, CS; Maitland, ME; Gilliam, LK; Phan, TH; Sweet, IR; Radtke, JR; Bota, V; Ransom, BR; Hirsch, IB ; ... Hirsch, IB High titers of autoantibodies to glutamate decarboxylase in type 1 diabetes patients: epitope analysis and inhibition of enzyme activity Endocr Pract 19 4: 663-8; 2013 PMC4037149

Larsson, HE; Jonsson, I; Lernmark, A; Ivarsson, S; Radtke, JR; Hampe, CS; Diabetes Prediction in Skane; Type 1 Diabetes Trial Network ; Decline in titers of anti-idiotypic antibodies specific to autoantibodies to GAD65 (GAD65Ab) precedes development of GAD65Ab and type 1 diabetes PLoS One 8 6: e65173; 2013 PMC3681789

Fernandez, R; Misra, R; Nalini, R; Hampe, CS; Ozer, K; Balasubramanyam, A ; Characteristics of patients with ketosis-prone diabetes (KPD) presenting with acute pancreatitis: implications for the natural history and etiology of a KPD subgroup Endocr Pract 19 2: 243-51; 2013

Cheramy, M; Hampe, CS; Ludvigsson, J; Casas, R ; Characteristics of in-vitro phenotypes of glutamic acid decarboxylase 65 autoantibodies in high-titre individuals Clin Exp Immunol 171 3: 247-54; 2013 PMC3569531

Hampe, CS ; Protective role of anti-idiotypic antibodies in autoimmunity--lessons for type 1 diabetes Autoimmunity 45 4: 320-31; 2012

Skoglund, C; Cheramy, M; Casas, R; Ludvigsson, J; Hampe, CS ; GAD autoantibody epitope pattern after GAD-alum treatment in children and adolescents with type 1 diabetes Pediatr Diabetes 13 3: 244-50; 2012 PMC3903414

Hampe, CS ; B Cell in Autoimmune Diseases Scientifica (Cairo) 2012 2012 PMC3692299

Wang, X; Zhang, A; Liu, Y; Chen, S; Feng, Z; Shang, W; Maziarz, M; Radtke, J; Hampe, CS ; ... Hampe, CS Anti-idiotypic antibody specific to GAD65 autoantibody prevents type 1 diabetes in the NOD mouse PLoS One 7 2: e32515; 2012 PMC3286479

Oak, S; Radtke, J; Torn, C; Landin-Olsson, M; Hampe, CS ; Immunoglobulin subclass profiles of anti-idiotypic antibodies to GAD65Ab differ between type 1 diabetes patients and healthy individuals Scand J Immunol 74 4: 363-7; 2011 PMC3855415