Cutting-edge research into the non-atherosclerotic complications of diabetes and aging is being conducted by DERC Affiliates from many departments, spanning diverse scientific disciplines. Where significant research overlaps exist, the work of some of these Affiliates is also listed under other Research Bases. For example, Affiliates whose projects include the DCCT/EDIC, DPP, Look AHEAD, Japanese-American, and FIND studies, all of which examine diabetic complications, are listed both here and in the Clinical Trials section of the Research Base.
| Principal Investigator |
DERC Project |
| Lydia Aguilar-Bryan, M.D., Ph.D. |
Molecular Basis for Hyperinsulinemic Hypoglycemia and Neonatal Diabetes in Newborns and Infants |
| Christine Abrass, M.D. | Pathogenesis of Diabetic Nephropathy
Glomerular Endothelial Cell Function in Diabetes
Growth Factors and Mesangial Cell Function |
| Salwa Al-Noori, Ph.D. |
Dentate Gyrus Modulation of the Counter Regulatory Response to Recurrent Hypoglycemia |
| Charles Alpers, M.D. | Development of a New Murine Model of Diabetic Nephropathy |
| Edward Boyko, M.D. | A Prospective Study of Endothelial Dysfunction and Diabetic Foot Ulcer Risk
The Epidemiology of Foot Structure and Ulceration in Diabetic Veterans |
| Kanchan Chitaley, Ph.D. |
Erectile Dysfunction in Type 2 Diabetes: Role of Adiponection |
| David Cook, Ph.D. |
The Role of the Liver and Insulin Resistance in Regulating Peripheral A-Beta Clearance |
| Kevin Conley, Ph.D. | Muscle Metabolism and Energetics in Type 2 Diabetes |
| Suzanne Craft, Ph.D. | Insulin-Mediated Memory Facilitation in Alzheimer's Disease
Insulin, Neurogenetics and Memory in Alzheimer's Disease: A Novel Therapeutic Approach
Glucose Regulation and Memory in Alzheimer's Disease
Insulin Resistance & CNS Function in T2DM
The Effects of Rosiglitazone in Patients with MCI
Therapeutic Effects of Intranasal Insulin in AD |
| Raghu Durvasala, M.D. |
Role of a Local Angiotensin System in Mediating Podocyte Injury in Diabetic Nephropathy (P&F) |
| Lucas Hoffman, M.D., Ph.D. |
Mechanisms of Bacterial Antibiotic Resistance and Pathogenesis in Cystic Fibrosis |
| James Hurley, Ph.D. |
Control of Photorecepter Metabolism |
| Elizabeth Kirk, Ph.D. |
Dietary Iron and Gene Regulation in Mice
|
| Dianne Figlewicz-Lattemann, Ph.D. | Regulation of Brain Catecholamines by Insulin in Normal, Diabetic, and Obese Rats |
| William Ledoux, Ph.D. |
Changes in the Characteristics of Plantar Soft Tissue with Diabetes |
| Martin Kushmerick, M.D., Ph.D. | Mitochrondrial Redox Quantification in Fast and Slow Twitch Murine Muscle |
| Junko Oshima, Ph.D. |
Impact of Haploinsufficiency in the Geriatric Population |
| Nicole Sanders, Ph.D. |
Central Nervous System Mechanism of Defective Hypoglycemia Counterregulation |
| Desmond Schatz, M.D. |
Autologous Cord Blood Transfusion to Reverse Hyperglycemia in Children with Type 1 Diabetes -- A Pilot Study |
| Michael Sobel, M.D., FACS |
Platelet Involvement in Inflammation and Thrombosis |
| Sum Ping Lee, M.D., Ph.D. | Epidemiology of Gallbladder Sludge and Stones in Pregnancy
|
| John Olerud, M.D. | The Roles for the Neurologic System and Laminin 5 in Wound Healing |
| Jerry Palmer, M.D. | Diabetes Control and Complications: Epidemiology of Diabetes Intervention and Complications (DCCT/EDIC) |
| Gayle Reiber, M.D. | Treatment Strategies for Patients with Diabetes at High Risk of Limb Loss |
| Kristina Utzschneider, M.D. |
Insulin Resistance in Non-Alcoholic Steatohepatitis |
| Hunter Wessells, M.D. | Mechanisms of Diabetes Associated Penile Endothelial Dysfunction
Neural Melanocortin Signaling and Erectile Function |