Clinical Trials & Epidemiological Studies
Many departments and divisions in the University of Washington have a long history of major accomplishments in clinical research, clinical trials, and all aspects of translational research. As reflections of this, DERC Affiliate Investigators have in the past and continue to participate in most of the major clinical trials in diabetes in the United States. DERC Affiliate Investigators frequently assume leadership positions, direct clinical centers, and/or direct core laboratories and chair and serve on numerous committees for these trials. The strength of this area of the research base is documented by the following table, which lists the Affiliate Investigators that are PIs or directors of clinical trials or epidemiological studies at the University of Washington.
| Principal Investigator | DERC Project |
| Melissa Austin, Ph.D. | Multi-Center Study of Pancreatic Cancer Etiology |
| Gail Bond, R.N., Ph.D. |
Telehealth for Diabetes Self-Management |
| William Bremner, M.D., Ph.D. | Hormone Contraception & Control of Testicular Function |
| John Brunzell, M.D. | Central Obesity Syndrome in a Subset of T1DM |
| Darcy Carr, M.D. | Insulin Sensitivity, Hemodynamics, & Endothelial Function in Women with a History of Preeclampsia |
| Suzanne Craft, Ph.D. | Insulin Resistance & CNS Function in T2DM
Insulin, Neurogenetics & Memory in Alzheimer's Disease: A Novel Therapeutic Approach
The Effects of Rosiglitazone in Patients with MCI
Therapeutic Effects of Intranasal Insulin in AD |
| Glen E. Duncan, Ph.D. | Kinetics of Human Homocysteine Metabolism |
| Sudha Iyengar, Ph.D. | Linkage Consortium End-Stage Renal Disease |
| Carla Greenbaum, M.D. | Juvenile Diabetes Research Foundation International Center for Translational Research Clinical Core |
| William Hagopian, M.D., Ph.D. | Prediction Pathogenesis & Prevention of T1D in the General Population |
| Gail Jarvik, Ph.D. | Family Studies of Lipoproteins & Coronary Disease |
| Steven Kahn, M.B., Ch.B. |
Diabetes Prevention Program/DPPOS
Look Ahead - A Study of the Effect of Weight Loss on Health Outcomes in Subjects with T2DM |
| Robert Knopp, M.D. | Effects of Insulin, Resistance on the Lipoprotein Response to Egg Feeding
Diets for Dyslipidemia in the Metabolic Syndrome |
| Ake Lernmark, Ph.D. | Type 1 Diabetes Immunogenetics |
| Santica Marcovina, Ph.D. | Northwest Lipid Metabolism and Diabetes Research Laboratories |
| Marguerite McNeely, M.D., M.P.H. | Predictors & Correlates of Visceral Adiposity |
| Jerry Palmer, M.D. | Diabetes Control & Complications: Epidemiology of Diabetes Intervention & Complications (DCCT/EDIC)
Pathogenesis & Prevention of T1DM
Trial Net Core Laboratories |
| Catherine Pihoker, M.D. | SEARCH for Diabetes in Youth of the Puget Sound |
| Elaine Tsai, M.D., M.P.H. | Identifying Risk Factors for Impaired Glucose Tolerance & Diabetes in Veterans with Central Obesity
Predictors of Subclinical Hepatic Steatosis in the Metabolic Syndrome |
| Scott Weigle, M.D. | Effect of Diet Composition on Body Weight Regulation
Increased Omega-3 Fatty Acid Intake in the Treatment of Obesity |
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