Our research is focused on the molecular and cellular mechanisms that cause Duchenne (DMD) and other muscular dystrophies and myopathies. We use the information gained from this basic research to identify signaling pathways that are dysfunctional in dystrophic muscle and are potential therapeutic targets for treatment of these devastating diseases.
The goal of our studies is to repurpose existing drugs that are already approved for use in humans for other diseases. Also, we are interested in developing new drugs that will slow muscle degeneration and heart failure to improve the quality of life, increase longevity and reduce the disease burden of DMD.
Department of Physiology & Biophysics
University of Washington School of Medicine
1750 NE Pacific Street
H418 HSB, Box 357290
Seattle, Washington 98195-7290