Ofer Yanay, MD
Associate Professor, Department of Pediatrics
Email Address: email@example.com
Department of Pediatrics Website: http://www.washington.edu/medicine/pediatrics/home/
Dr. Yanay is an attending physician in the Division of Pediatric Critical Care and the Medical Co-Director of Respiratory Care at Seattle Children’s Hospital. He has published chapters and peer-reviewed articles with emphasis on gene therapy.
Dr. Yanay’s research has focused on lentivirus-based vectors and on gene therapy–based treatment for diabetes. His current work is directed at evaluating the role of glucose regulatory hormones in controlling inflammation in sepsis.
Whalen LD, Di Gennaro JL, Irby GA, Yanay O, Zimmerman JJ. Long-Term Dexmedetomidine Use and Safety Profile Among Critically Ill Children and Neonates. Pediatr Crit Care Med. In Press, 2014
von Saint Andre-von Arnim A, Farris R, Roberts JS, Yanay O, Brogan TV, Zimmerman JJ. Common endocrine issues in the pediatric intensive care unit. Crit Care Clin.29:335-358, 2013
Yanay O, Dale DC, Osborne WR.Repeated lentivirus-mediated granulocyte colony-stimulating factor administration to treat canine cyclic neutropenia. Hum Gene Ther. 23:1136-1143, 2012
Moralejo D, Yanay O, Kernan K, Bailey A, Lernmark A, Osborne W. Sustained glucagon-like peptide 1 expression from encapsulated transduced cells to treat obese diabetic rats. J Biosci Bioeng. 111:383-387, 2011
Yanay O, Moralejo D, Kernan K, Brzezinski M, Fuller JM, Barton RW, Lernmark A, Osborne WR. Prolonged survival and improved glycemia in BioBreeding diabetic rats after early sustained exposure to glucagon-like peptide 1. J Gene Med. 12:538-544, 2010.
Sweet IR, Yanay O, Waldron L, Gilbert M, Fuller JM, Tupling T, Lernmark A, Osborne WR. Treatment of diabetic rats with encapsulated islets. J Cell Mol Med. 12:2644-2650, 2008
Brzezinski M, Yanay O, Waldron L, Barry SC, Osborne WR. G-CSF-lentivirus administration in rats provided sustained elevated neutrophil counts and subsequent EPO-lentivirus administration increased hematocrits. J Gene Med. 9:571-578, 2007.
Yanay O, Brzezinski M, Christensen J, Liggitt D, Dale DC, Osborne WR. An adult dog with cyclic neutropenia treated by lentivirus- mediated delivery of granulocyte colony-stimulating factor. Hum Gene Ther. 17:464-469, 2006
Barry S, Brzezinski M, Yanay O, Seppen JE, Osborne WR. Sustained elevation of neutrophils in rats induced by lentivirus-mediated G-CSF delivery. J Gene Med. 7:1510-1516, 2005.
Yanay O, Brogan TV, Martin LD. Continuous pentobarbital infusion in children is associated with high rates of complications. J Crit Care. 19:174-178, 2004.
Yanay O, Lerman-Sagie T, Gilad E, Nissenkorn A, Jaferi J, Watemberg N, Houri S. Infant botulism in Israel: knowledge enables prompt diagnosis. Isr Med Assoc J. 6:249-250, 2004.
Yanay O, Barry SC, Flint LY, Brzezinski M, Barton RW, Osborne WR. Long-term erythropoietin gene expression from transduced cells in bioisolator devices. Hum Gene Ther. 14:1587-1593, 2003.
Yanay O, Barry SC, Katen LJ, Brzezinski M, Flint LY, Christensen J, Liggitt D, Dale DC, Osborne WR. Treatment of canine cyclic neutropenia by lentivirus-mediated G-CSF delivery. Blood. 102:2046-2052, 2003.
Yanay O, Vaughan DJ, Diab M, Brownstein D, Brogan TV. Retained wooden foreign body in a child’s thigh complicated by severe necrotizing fasciitis: a case report and discussion of imaging modalities for early diagnosis. Pediatr Emerg Care. 17:354-355, 2001.
Vaughan D, Yanay O, Zimmerman JJ. Deciphering the oxyradical inflammation Rosetta stone: O2*-NO*, OONO-, polymorphonuclear neutrophils, poly(ADP-ribose) synthetase, systemic inflammatory response syndrome, and multiple organ dysfunction syndrome. Crit Care Med. 27:1666-1669, 1999.
Within the Diabetes and Obesity Center of Excellence and its Affiliated Members
William Osborne, PhD
Outside of the Diabetes and Obesity Center of Excellence
Jerry Zimmerman, MD, PhD