Study Name: Insulin resistance in non-alcoholic fatty liver disease
If you have been diagnosed with non-alcoholic fatty liver you may be interested in being part of a research study investigating why people get fatty liver disease and the link between fatty liver and abnormal glucose metabolism.
What is fatty liver disease? This is a condition where fat accumulates in the liver. It is more common in people who are overweight or obese and is associated with insulin resistance and diabetes. Fatty liver is usually suspected when a blood test shows elevated liver enzymes and other causes have been excluded.
How is fatty liver diagnosed? Fat in the liver can be diagnosed by simple imaging studies such as ultrasound or CT scan.
Can fatty liver progress to more serious liver disease? To determine if there is liver injury a liver biopsy is necessary. If the liver biopsy shows that there is inflammation and destruction of liver cells, sometimes along with scarring (fibrosis), this is called non-alcoholic steatohepatitis or NASH. NASH is more serious as the scarring could progress to liver cirhhosis and liver failure in a small percentage of patients.
This study is being conducted by investigators at the University of Washington and the VA Puget Sound Medical Center.
For more information about the study, contact:
Kristina Utzschneider, MD 206-277-3568