Department of Veterans Affairs  •   Puget Sound Health Care System  •  American Lake & Seattle

University of Washington Diabetes Research Group

Study Details: Insulin resistance in non-alcoholic fatty liver disease

What does the study involve?

  • Screening visit to see if you are eligible for the study
  • 3 days of study procedures to measure body fat, insulin resistance and glucose metabolism – these studies involve iv's, administration of glucose and insulin, and low doses of radiation (x-ray tests). Two of the study days are during the morning and the 3rd study day involves staying overnight.
  • 6 months medication: After the initial study procedures, subjects are given medications to take for 6 months. Medications include: pioglitazone (a medication used to treat diabetes), fenofibrate (a medication used to treat cholesterol and triglycerides) or placebo (dummy tablets). Which medication you receive is determined randomly (like flipping a coin) and neither you nor the investigator will know which medication you are on. This is to make sure there is no bias in the results.
  • Monthly safety visits while taking medication
  • Repeat 3 days of study procedures after the 6 month medication

Who is eligible?

If you have been diagnosed with fatty liver (either by imaging study or by liver biopsy) and you do not drink more than 2 alcoholic drinks a day you may be eligible.

click here to see if you qualify

Compensation:

Subjects can receive up to $625 for participation

study contact:

For more information about the study, contact:

Kristina Utzschneider, MD 206-277-3568