UWMC/HMC

Drug Formulary Changes (Archives)

April 1997 - March 1998

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The following table shows changes occuring after the 1997/98 Drug Formulary went to press.

Formulary Action and Date (Unless otherwise noted, formulary changes became effective on the 1st day of the following month.)	Generic and Trade Name	Dosage Form(s) and Strength(s)	Therapeutic Classification	Use (Comment)
Deleted: 2/17/98	Adsorbable collagen (Helitene)	Powder: 1g	Hemostatic	(Replaced by: Avitene)
Added: 3/17/98	Alatrofloxacin (Trovan IV) Also see: Trovafloxacin	Injection: 5mg/mL (40mL, 60mL)	Fluoroquinolone antibiotic	Pneumonia; bronchitis; sinusitus; UTI; prostatitis; gonorrhea; cervicitis; PID; skin, intra-abdominal, gynecologic, and pelvic infections; surgical prophylaxis
Added: 8/19/97	Anagrelide (Agrylin)	Capsule: 0.5mg	Antiplatelet agent	Essential thrombocythemia
Added: 6/17/97	Atorvastatin (Lipitor)	Tablet: 10mg, 20mg	HMG-CoA reductase inhibitor	Hypercholesterolemia
Added: 11/18/97	Azithromycin (Zithromax)	Injection: 500mg	Macrolide antibiotic	Community-acquired pneumonia, PID
Added: 9/16/97	Baclofen (generic)	Tablet: 10mg, 20mg	Centrally-acting skeletal muscle relaxant	Spasticity
Deleted: 9/16/97	Baclofen (Lioresal)	Tablet: 10mg, 20mg	Centrally-acting skeletal muscle relaxant	(Replaced by: generic tablets)
Added: 5/20/97	Brimonidine (Alphagan)	Ophthalmic Solution: 0.2% (5mL)	Alpha-2 receptor agonist	Reduction of intraocular pressure
Added: 6/17/97	Bupropion (Wellbutrin SR)	Tablet, sustained release: 100mg, 150mg	Antidepressant	Depression
Added: 6/17/97	Bupropion (Zyban)	Tablet, sustained release: 150mg	Antidepressant	Smoking cessation
Added: 9/16/97	Calcitonin-salmon (various)	Injection: 200 IU/mL (2mL)	Peptide hormone	Hypercalcemia
Added: 11/18/97	Carmustine (Gliadel)	Wafer: 7.7mg	Chemotherapeutic alkylating agent	Recurrent glioblastoma
Added: 9/16/97	Carvedilol (Coreg)	Tablet: 3.125mg, 6.25mg, 12.5mg, 25mg	Alpha/beta adrenergic blocker	Hypertension
Added: 1/20/98	Cellulose, oxidized (Oxycel)	Pleget: 2" x 1" x 1"; Pad: 3" x 3"	Topical hemostatic	Intra-operative hemostasis
Added: 8/19/97	Clonidine (Duraclon)	Epidural injection: 1mg/10mL	Central alpha adrenergic agonist	Intractable pain
Added: 8/19/97	Cortecorelin ovine triflutate (Acthrel)	Injection: 100mcg/2mL	Diagnostic aid	Diagnosis of ACTH-dependent Cushing's
Deleted: 8/19/97	Crotamiton (Eurax)	Cream; Lotion: 10%	Scabacide	(Replaced by: lindane and permethrin)
Added with a Level II Restriction: 2/17/98	Danaparoid (Orgaran)	Injection: 750 anti-factor Xa units/0.6mL	Antithrombotic	Prophylaxis of pulmonary thromboembolism and DVT. (Limited to use in patients with known or suspected heparin-induced thrombocytopenia and who have received a hematology consult.)
Added: 6/17/97	Delavirdine (Rescriptor)	Tablet: 100mg	HIV non-nucleoside reverse transcriptase inhibitor	HIV infection
Manufacturer discontinuation: 9/15/97	Dexfenfluramine (Redux)	Capsule: 15mg	Appetite suppressant	Obesity
Added: 6/17/97	Dextroamphetamine (Dexedrine Spansules)	Capsule, sustained release: 5mg, 10mg, 15mg	CNS stimulant	Attention deficit disorders; Narcolepsy
Added: 5/20/97	Donepezil (Aricept)	Tablet: 5mg, 10mg	Reversible cholinesterase inhibitor	Alzheimer's disease (Replaces: tacrine)
Added: 6/17/97	Erythromycin ethylsuccinate and sulfisoxazole (Pediazole)	Oral Suspension: erythromycin 200mg & sulfisoxazole 600mg/5mL (100mL, 200mL)	Macrolide & sulfonamide antibiotic combination	Acute otitis media in children
Added: 4/15/97	Estradiol (Estring)	Vaginal Ring: 2mg	Estrogen	Urogenital symptoms associated with menopause
Manufacturer discontinuation: 9/15/97	Fenfluramine (Pondimin)	Tablet: 20mg	Appetite suppressant	Obesity
Added: 5/20/97	Ferumoxides (Feridex)	Injection: 11.2mg iron/mL (5mL)	MRI contrast media	Liver imaging
Added: 2/17/98	Ioxaglate (Hexabrix)	Injection: meglumine 39.3% + sodium 19.6% (100mL)	Ionic contrast agent	Contrast enhancement
Added: 8/19/97	Ipratropium bromide/albuterol (Combivent)	Inhaler: 14.7g (200 inhalations)	Combination beta-2 agonist & anticholinergic	COPD
Added: 8/19/97	Ivermectin (Stromectrol)	Tablet: 6mg	Antiparasitic agent	Onchocerciasis, strongyloidiasis, scabies
Added: 11/18/97	Lactase (LactAid Ultra)	Tablet: 9000 units	Dietary supplement	Lactose intolerance
Added: 5/20/97	Latanoprost (Xalatan)	Ophthalmic Solution: 0.005% (2.5mL)	Selective prostanoid FP receptor agonist	Reduction of intraocular pressure
Added: 5/20/97	Levofloxacin (Levaquin)	Injection; Tablet: 250mg, 500mg	Fluoroquinolone antibiotic (L-isomer of ofloxacin)	Sinusitis, bronchitis, pneumonia, skin infections, UTI, pyelonephritis (Replaces: ofloxacin)
Added: 9/16/97	Levonorgestrel 100mcg & ethinyl estradiol 20mcg (Alesse)	Tablet: 28-day pack	Oral contraceptive	Prevention of pregnancy
Deleted: 6/17/97	Lovastatin (Mevacor)	Tablet: 10mg, 20mg, 40mg	HMG-CoA reductase inhibitor	(Replaced by: atorvastatin, pravastatin, and simvastatin)
Deleted: 3/17/98	Loxapine (Loxitane)	All dosage forms and strengths	Antipsychotic	(Low usage agent)
Line Item Extension Added: 6/17/97	Luprolide (Leupron Depot - 3 Month)	Injection: 22.5mg	Gonadotropin-releasing hormone analog	Prostate cancer
Deleted: 3/17/98	Mesoridazine (Serentil)	All dosage forms and strengths	Antipsychotic	(Low usage agent)
Added: 6/17/97	Methylphenidate (Ritalin SR)	Tablet, sustained release: 20mg	CNS stimulant	Attention deficit disorders
Added: 3/17/98	Minocycline (Minocin)	Capsule: 50mg, 100mg	Tetracycline antibiotic	Hansen's disease; various other infections
Added: 10/27/97	Mirtazapine (Remeron)	Tablet: 15mg, 30mg	Tetracyclic antidepressant	Depression
Deleted: 3/17/98	Molindone (Moban)	All dosage forms and strengths	Antipsychotic	(Low usage agent)
Added: 4/15/97	Nelfinavir (Viracept)	Tablet: 250mg; Powder for Oral Solution: 144g	HIV protease inhibitor	HIV infection
Manufacturer Discontinuation: 5/20/97	Niclosamide (Niclocide)	Tablet: 500mg	Anthelmintic	(Replaced by: praziquantel)
Added: 1/20/98	Nifedipine (AdalatCC)	Tablet: 30mg, 60mg, 90mg	Calcium channel blocker	Angina; Hypertension
Deleted: 3/17/98	Ofloxacin (Floxin)	Tablet	Fluoroquinolone antibiotic	(Replaced by: levofloxacin)
Added: 8/19/97	Oxandrolone (Oxandrin)	Tablet: 2.5mg	Anabolic Steroid	Weight gain following surgery/trauma
Manufactuter discontinuation: 3/17/98	Pentobarbital (Nembutal)	Injection: 100mg/2mL; Suppository: 30mg	Barbiturate	Sedative-hypnotic; anticonvulsant
Added: 1/20/98	Pramipexole (Mirapex)	Tablet: 0.125mg, 0.25mg, 1mg, 1.5mg	Non-ergot dopamine agonist	Parkinson's disease
Added: 6/17/97	Pravastatin (Pravachol)	Tablet: 10mg, 20mg, 40mg	HMG-CoA reductase inhibitor	Hypercholesterolemia
Added: 2/17/98	Procainamide (ProcanSR)	Tablet, sustained release: 250mg; 750mg; 500mg	Antiarrhythmic	Ventricular arrhythmias
Added: 2/17/98	Progesterone (Crinone)	Vaginal gel: 8% (2.6g)	Steroid (progesterone)	Infertility
Added: 3/17/98	Quetiapine (Seroquel)	Tablet: 25mg, 100mg, 200mg	Atypical antipsychotic	Psychoses
Added: 9/16/97	Ranitidine & bismuth citrate (Tritec)	Tablet: 400mg	Combination H-2 blocker & anti-Helicobacter pylori agent	Duodenal ulcer associated with H. pylori
Added: 4/15/97	Reteplase (Retavase)	Injection Kit: 10 unit (#2)	Recombinant plasminogen activator	Acute MI
Added: 1/20/98	Ropinirole (Requip)	Tablet: 0.25mg, 0.5mg, 1mg, 2mg, 5mg	Non-ergot dopamine agonist	Parkinson's disease
Added: 4/15/97	Ropivacaine (Naropin)	Injection: 0.2% (20mL, 100mL); 0.5% (30mL); 0.75% (20mL); 1% (10mL, 20mL)	Local anesthetic (amide type)	Local anesthesia
Added: 2/17/98	Sumatriptan (Imitrex)	Spray, nasal: 5mg, 20mg	Selective Serotonin (5HT1) receptor agonist	Migraine
Deleted: Effective 11/1/97	Tacrine (Cognex)	Tablet: 10mg, 20mg, 30mg, 40mg	Reversible cholinesterase inhibitor	(Replaced by: donepezil)
Added: 1/20/98	Terbinafine (Lamisil)	Cream: 1% (15g, 30g)	Topical antifungal	Tinea corporis, cruris, pedis
Added: 3/17/98	Tiagabine (Gabatril)	Tablet: 4mg, 12mg, 16mg, 20mg	Anticonvulsant	Partial seizures
Added: 5/20/97	Tizanidine (Zanaflex)	Tablet: 4mg	Centrally-acting alpha-2 receptor agonist	Spasticity
Added: 6/17/97	Topiramate (Topamax)	Tablet: 25mg, 100mg, 200mg	Anticonvulsant	Partial onset seizures
Deleted: 3/17/98	Trifluoperazine (Stelazine)	All dosage forms and strengths	Antipsychotic	(Low usage agent)
Added: 11/18/97	Troglitazone (Rezulin)	Tablet: 200mg, 300mg, 400mg	Thiazolidinedione antidiabetic agent	Type II diabetes
Added: 3/17/98	Trovafloxacin (Trovan) Also see: alatrofloxacin	Tablet: 100mg, 200mg	Fluoroquinolone antibiotic	Pneumonia; bronchitis; sinusitus; UTI; prostatitis; gonorrhea; cervicitis; PID; skin, intra-abdominal, gynecologic, and pelvic infections; surgical prophylaxis
Line Item Extension Added: 6/17/97	Urofollitropin (Fertinex)	Injection: 75units	Ovulation stimulant	Infertility; Assisted reproductive technologies (Replaces: Metrodin)
Manufacturer Discontinuation: 6/17/97	Urofollitropin (Metrodin)	Injection: 75units	Ovulation stimulant	(Replaced by: Fertinex)
Line Item Extension Added: 6/17/97	Valproic acid (Depacon)	Injection: 5mL	Anticonvulsant	Epilepsy
Added: 9/16/97	Valsartan (Diovan)	Capsule: 80mg, 160mg	Angiotensin II receptor antagonist	Hypertension

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