The laboratory of David Russell

At the University of Washington

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Lab Mission: Total Control of the Human Genome

The Russell lab is developing improved methods for manipulating the mammalian genome, with the goal of creating new genetic therapies. Our interests include viral vectors, stem cells and genetic diseases. We have made contributions in the fields of rAAV vectors, foamy virus vectors, vector integration, gene targeting, insertional mutagenesis, and the genetic manipulation of stem cells. A major current focus is the use of rAAV for gene editing in human pluripotent stem cells, including efforts to engineer universal donor cells for regenerative medicine applications.