In a seminar session, one second-year master’s student from each of the academic programs was selected to present an oral summary of his or her thesis research. The remainder of the graduating master’s students and selected PhD students presented posters of their work. Thesis abstracts are online. Faculty preceptors are listed in parentheses.
Modulating Toxicity
Karen L. Jansen, MS, Toxicology (Lucio Costa)
Paraoxonase (PON1) is an enzyme that protects people from
the toxic effects of organophosphorus insecticides. Genetic
differences in PON1 can affect how toxic the pesticide might
be for an individual. This study exposed mice of different
PON1 genotypes to metabolites of the insecticides chlorpyrifos,
diazinon, and malathion. PON1 genotype greatly
influenced the interaction among the three metabolites by
altering the inhibition of another organophosphate detoxifying
enzyme, carboxylesterase. This has implications for
exposure of people to mixtures of pesticides.
Optical Remote Sensing
Christopher D. Miele, MS, Industrial Hygiene (Michael Yost)
Particulate air pollution is an environmental and occupational health risk because these fine particles pass through the nose and throat and penetrate deep into lung tissue. Diesel particulate matter is among the highest priorities of the Puget Sound Clean Air Agency. This feasibility study used an optical remote sensing technique, ultraviolet differential
optical absorption spectroscopy, to measure multiple air pollutants in an open path over Interstate 5 in downtown Seattle. The Clean Air Agency already uses this technique for monitoring gases, and this study tested its feasibility for monitoring particle concentration.
Seasonal Pesticide Application
Lisa A. Tolbert, MS, Environmental Health (Michael Yost)
As residential growth has expanded into agricultural areas,
concerns have arisen about pesticide drift into nearby
communities. This pilot study indicates that pesticide levels
vary significantly over time but do not vary significantly by
location. This suggests that future air monitoring should
sample frequently enough to capture day-to-day variations
in pesticide concentrations, but not necessarily focus on
location, because the community air shed appears to be
well-mixed.
Traffic-Related Air Pollution
Victor Van Hee, MPH, Occupational and Environmental Medicine (Joel Kaufman)
Epidemiologic studies have linked heart disease and death
with particulate air pollution, but the mechanisms remain
unclear. This study looked at two changes generally associated
with congestive heart failure, increased left ventricular mass
index (LVMI) and decreased ejection fraction (EF). Analyzing
data from the Multi-Ethnic Study of Atherosclerosis (MESA)
Air Pollution Study, he found that people living within 50
meters of a major roadway had a significant increase in LVMI.
Though not statistically significant, the effect was larger for
Hispanics, African Americans, smokers, diabetics, and men.
The LVMI appears to be a more sensitive indicator than EF.
STUDENT POSTER SESSION
Environmental Health, MS
Clarita Lefthand (John Scott Meschke) Identification of
the source of fecal contamination in Tulalip Bay with
bacteroides 16S rRNA gene and F+ specific coliphage
markers
Photo by Cathy Schwartz.
Alison C. Scherer (Elaine Faustman) Comparative analysis of fish consumption advisories to pregnant women and
women of childbearing age
Leah D. Tivoli (John Scott Meschke) Clostridium perfringens: A reservoir of antibiotic resistance genes in the
environment?
Industrial Hygiene, MS
Stephanie C. Griffin (Noah Seixas) Indicators of hearing
protection use: Self report and research observation
Christopher J. Jacomme (Michael Morgan) Field evaluation
of a two-zone model used to predict workplace air
contaminant concentrations
Toxicology, MS
Steve Krival (Terrance Kavanagh) Principal components
analysis of liver tissue metabolites in male glutamatecysteine
ligase transgenic and wildtype mice treated with
acetaminophen
Li Li (Lucio Costa) Protective role of carbachol in domoic
acid-induced apoptosis in cerebellar granule neurons
Environmental and Occupational Health, MPH
Janessa Graves (William Daniell) Fluoride and dental
fluorosis on San Juan Island, Washington
Erin M. O’Brien (Joel Kaufman) Gene-environment interactions
in the Multi-Ethnic Study of Atherosclerosis
and Air Pollution (MESA Air)
Brian D. Smith (John Scott Meschke) The effect of surface
charge, negative and bipolar ionization on the
deposition of airborne bacteria
Michelle M. Sommargren (Richard Fenske) Reducing
childhood pesticide exposure by targeting the clinician
pesticide training gap: The design, implementation and
evaluation of an online curriculum
Joyce Tseng (Matthew Keifer) Impact evaluation of a
farmworker environmental and occupational health
community-based participatory research course in the
Yakima Valley, Washington
Douglas A. Badzik (William Daniell) Hearing loss in US
Army aviators, comparing 2005 to 2001
Ingeborg Cox (Matthew Keifer) Testing validity of audio
computer assisted self interview (ACASI) among illiterate
and low literate pesticide handlers
Michael J. Sigmon (William Daniell) Where there’s smoke,
is there disease? A study of environmental airborne
exposures in soldiers returning from Iraq
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