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Distinguished Visiting Epidemiologist

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Special Seminar
Wednesday, May 18th
3:30 to 4:50pm
South Campus Center 316L

“Herd Immunity: big ideas evolve….”

Dr. Fine  

Dr. Paul E. M. Fine

Department of Infectious Disease Epidemiology
London School of Hygiene and Tropical Medicine



Paul Fine trained originally in zoology and veterinary medicine in the United States, and then in parasitology and epidemiology  in the UK. He then worked in the smallpox eradication program in India and spent a year at U/C Berkeley working on arboviruses, before joining the staff of the London School of Hygiene and Tropical Medicine in 1976. His major research interests have been in infection dynamics, family studies, genetics, and in the evaluation of vaccine efficacy, effectiveness, adverse reactions and impact, applied to a variety of infections. Much of his earlier work concentrated upon vertical (from parent to progeny) transmission of infections and upon measles and pertussis in the UK. He directed a large epidemiological research programme (the "Karonga Prevention Study") in Malawi from 1978-2006, concentrating at first upon leprosy, then tuberculosis, and ultimately HIV, and including demographic surveillance, vaccine evaluation, and studies of other infections in a rural population in northern Malawi.  Since 1997 his interest in vaccines has broadened to include the implications of the transmissibility of oral polio vaccine virus for the global polio eradication programme, the assessment and implications of “non-specific effects” of vaccines, and procedures for the optimization of vaccination schedules in developing countries.

The term “herd immunity” is used widely, but not always consistently, in discussions of the population impact of vaccines. It raises a variety issues relating to major vaccination programs today.  The talk will trace the concept’s logic, controversies and implications, emphasising the circumstances which have driven its development, including important contributions made by John Fox, Professor of Epidemiology at the University of Washington.

Suggested reading
Fine PEM, Eames K, Heymann DL. “Herd immunity”: a rough guide”. Clinical Infectous Diseases 2011; 52: 911–916.

Individual meetings: To schedule a time to meet with Dr. Fine on March 18th, 10:00 am-12:00 pm, in F257 Epi Conference Room, please email ekantor@uw.edu

Additional Events:

JOURNAL CLUB: “The polio eradication ‘endgame’ – with particular reference to vaccine-derived polioviruses”
Tuesday, May 17th, 12:30-1:20pm
F257 Epi Conf Room
Lunch provided

PANEL DISCUSSION: Vaccination Strategies and Controversies:The Bumpy Road from ProgramImplementation towards Eradication
Tuesday, May 17, 2011, 3:30 - 4:50 pm
Foege Building, Genome Sciences S060
Reception immediately following

Flyer (pdf)

Updated on May 2, 2011