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Mario Kratz, PhD, MSc

Research Associate Professor, Epidemiology
Adjunct Research Associate Professor, Metabolism

Associate Member, Fred Hutchinson Cancer Research Center
Public Health Sciences Division, Cancer Prevention Program

Associate Director, University of Washington Diabetes Research Center
Immunology and Inflammation Core

Contact Information
Fred Hutchinson Cancer Research Center
Office: M4-B402
Box 358080
Public Health Sciences, Cancer Prevention Program
1100 Fairview Ave N, PO Box 19024
Seattle, WA 98109
Tel: 206-667-7362
Fax: 206-667-7850

Research Interests
Dr. Kratz’s research focuses on the relationship between diet, obesity, and chronic diseases such as type 2 diabetes, cardiovascular disease, and cancers associated with obesity. Current projects are either controlled dietary intervention studies in humans to better understand how diet composition affects glucose homeostasis and liver fat, or clinical studies that aim to understand the biological mechanisms linking diet, obesity and chronic disease. All of these studies focus on chronic low-grade systemic inflammation and adipose tissue inflammation, a major factor in the etiology of many chronic diseases.

Clinical Expertise 
Dr. Kratz has more than 15 years of experience conducting clinical studies in a variety of human populations.

PhD, Nutritional Science, University of Bonn (Germany) 2001
MSc, Nutritional Science, University of Bonn (Germany) 1996


  • Diet and Metabolic Inflammation (AIM) Study
  • Adipose Tissue Inflammation & Therapeutic Estrogen Suppression Trial (ATTEST)
  • The Impact of Low-fat and Full-fat Dairy Consumption on Glucose Homeostasis
  • Inflammation in Diabetes Etiology Assessment (IDEA) Study
  • Metabolically Activated Macrophage in Obesity & Insulin Resistance (MAC) Study

Selected Publications
Kremsdorf, RA, Hoofnagle AN, Kratz M, Weigle DS, Callahan HS, Purnell JQ, Horgan AM, de Boer IH, Kestenbaum BR. 2013. Effects of a high-protein diet on regulation of phosphorus homeostasis.. The Journal of clinical endocrinology and metabolism. 98(3):1207-13 Abstract

Campbell, KL, Foster-Schubert KE, Makar KW, Kratz M, Hagman D, Schur EA, Habermann N, Horton M, Abbenhardt C, Kuan L-Y et al.. 2013. Gene Expression Changes in Adipose Tissue with Diet- and/or Exercise-Induced Weight Loss.. Cancer prevention research (Philadelphia, Pa.). 6(3):217-31. Abstract

Kratz, M, Kuzma JN, Hagman DK, Van Yserloo B, Matthys CC, Callahan HS, Weigle DS. 2013. n3 PUFAs Do Not Affect Adipose Tissue Inflammation in Overweight to Moderately Obese Men and Women.. The Journal of nutrition. 143(8):1340-7. Abstract

In the news
Obesity and Cancer (Quest Online)
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