Vice Chair, Global Health
Professor, Allergy and Infectious Dis.
Professor, Global Health
EducationMD Medicine, University of Washington, 2003
PhD Epidemiology, University of Washington, 2001
BA Chemistry, Religious Studies, Washington University, 1995
International Clinical Research Center
908 Jefferson St.
Seattle, WA 98104
Dr. Baeten's research focuses on the prevention of HIV-1 and other sexually transmitted diseases, including clinical trials of novel prevention interventions, epidemiologic studies of risk factors for HIV-1 transmission, and behavioral, translational, and implementation science research aimed at optimizing prevention delivery. He led the Partners PrEP Study and MTN-020/ASPIRE, randomized clinical trials that demonstrated the efficacy of oral tenofovir-based pre-exposure prophylaxis (PrEP) and the dapivirine vaginal ring for protection against HIV-1 acquisition. Current projects include a) a multinational open-label trial of the dapivirine vaginal ring for HIV-1 prevention in women (MTN-025/HOPE, through the NIH Microbicides Trials Network), b) implementation science work to deliver antiretroviral treatment and PrEP for HIV-1 prevention, c) studies exploring use of hormonal contraception as a risk factor for HIV-1 (including co-chairing the ECHO Study), and d) collaborative studies of immunologic and virologic factors that influence HIV-1 transmission.
HIV/AIDS and other STDs; women; Africa
Heffron R, Donnell D, Rees H, Celum C, Mugo N, Were E, de Bruyn G, Nakku-Joloba E, Ngure K, Kiarie J, Coombs RW, Baeten JM for the Partners in Prevention HSV/HIV Transmission Study Team. Hormonal contraceptive use and risk of HIV-1 transmission: a prospective cohort analysis. Lancet Infectious Diseases 2012; 12:19-26. PMCID 3266951.
Hallett T, Baeten JM, Heffron R, Barnabas R, de Bruyn G, Cremin I, Delany S, Garnett GP, Gray G, Johnson L, McIntyre J, Rees H, Celum C. Optimal uses of antiretrovirals for prevention in HIV-1 serodiscordant heterosexual couples in South Africa: a modelling study. PLoS Medicine 2011; 8:e1001123. PMCID: PMC3217021.
Baeten JM, Kahle E, Lingappa JR, Coombs RW, Delany-Moretlwe S, Nakku-Joloba E, Mugo NR, Wald A, Corey L, Donnell D, Campbell MS, Mullins JI, Celum C, for the Partners in Prevention HSV/HIV Transmission Study Team. Genital HIV-1 RNA levels predict risk of heterosexual HIV-1 transmission. Science Translational Medicine 2011; 3:77ra29. PMCID: PMC3087186.
Donnell D, Baeten JM, Kiarie J, Thomas KK, Stevens W, Cohen CR, McIntyre J, Lingappa JR, Celum C, for the Partners in Prevention HSV/HIV Transmission Study Team. Heterosexual HIV-1 transmission after initiation of antiretroviral therapy: a prospective cohort study. Lancet 2010; 375: 2092-8. PMCID 2922041.
Baeten JM, Donnell D, Ndase P, Mugo NR, Campbell JD, Wangisi J, Tappero JW, Bukusi EA, Cohen CR, Katabira E, Ronald A, Tumwesigye E, Were E, Fife KH, Kiarie J, Farquhar C, John-Stewart G, Kakia A, Odoyo J, Mucunguzi A, Nakku-Joloba E, Twesigye R, Ngure K, Apaka C, Tamooh H, Gabona F, Mujugira A, Panteleeff D, Thomas KK, Kidoguchi L, Krows M, Revall J, Morrison S, Haugen H, Emmanuel-Ogier M, Ondrejcek L, Coombs RW, Frenkel L, Hendrix C, Bumpus N, Bangsberg D, Haberer JE, Stevens WS, Lingappa JR, Celum C, for the Partners PrEP Study Team. Antiretroviral prophylaxis for HIV prevention in heterosexual men and women. New England Journal of Medicine 2012; 367:399-410. PMCID 3770474.
In The News
Turning the tide on HIV
The Daily, 03/31/2016
Vaginal Ring Lowered HIV Rates in African Women
UW School of Public Health News, 02/25/2016
Vaginal ring reduces HIV risk in women
New England Journal of Medicine, 02/22/2016