Fetal Alcohol Spectrum Disorders (FASD) in Adults: Health and Behavior

Principal Investigators: Claire Coles, Ph.D. (Emory University, Atlanta, Georgia), Therese Grant Ph.D. (University of Washington, Seattle, Washington)

Co-Investigator Sandra Radin, Ph.D. (University of Washington, Seattle, Washington)

Dysmorphologist Margaret Adam, M.D.

Research Coordinators: Kathryn Kelly, B.A. and Tim Smith-Stewart, B.F.A.

Funded by NIH/NIAAA

07/01/17 through 06/30/22

Recent epidemiological studies suggest that Fetal Alcohol Spectrum Disorder (FASD) may have a prevalence of up to 5% in the population, however, it is rarely diagnosed in adulthood and there are no recognized treatment protocols because, despite decades of research on the effects of prenatal alcohol exposure, scientific study of adults with FASD is almost unknown.  The current NIH/NIAAA-funded research addresses this deficit with the following Specific Aims: 1) Establish a registry of 500 individuals, older than 30 years of age, with known alcohol exposure/FASD diagnosis or who are matched controls who will respond to a health survey, and who will be available for future studies; 2) Evaluate in depth current physical health, mental health, and functional status among affected individuals (FAS or FASD) and controls (120 from Seattle and 120 from Atlanta);  with the goal of refining diagnostic criteria for FASD in this age group and determining the persistence and severity of disability associated with PAE. and 3) Assess immune status in collaboration with Dr. Weinberg (University of British Columbia) and identify outcomes associated with health indicators.