Tag Archives: Leroy Hood

Paradigm shifts and P4 Medicine

Dr. Leroy Hood, a pioneer in the systems approach to biology and medicine, spoke at UW Foster School in January 2013 about innovation, complexity, P4 Medicine—predictive, preventative, personalized, and participatory—and much more.

Dr. Hood has played a role in founding more than fourteen biotechnology companies, including Amgen, Applied Biosystems, Darwin, and The Accelerator and Integrated Diagnostics. He is a member of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine. Of the 6,000+ scientists world-wide who belong to one or more of these academies, Dr. Hood is one of only fifteen people accepted to all three. Additionally, Dr. Hood has published more than 700 peer reviewed articles and currently holds 36 patents.

In a career of dramatic innovation, Dr. Hood has seen a number of paradigm shifts. He identified four common traits. Each paradigm change:

  1. Fundamentally altered how, in his case, scientists think about biology and the practice of biology.
  2. Faced enormous initial skepticism and, in some cases, actual hostility because there were perceived threats to the traditional way of getting things done.
  3. Forced the creation of new organizational structures—the bureaucracy that comes from existing organizational structures hurts the ability to change the way you think about something.
  4. Required enormous risk taking.

Watch the video below for more highlights from his talk, including how the Human Genome Project transformed biology, implications of P4 Medicine, and his thoughts on the future of systems biology.

Dr. Leroy Hood from Foster School of Business on Vimeo.

Leroy Hood was one of UW Foster School of Business Dean Jim Jiambalvo’s guest speakers at the annual Leaders to Legends Breakfast Lecture Series, which include notable leaders in an array of industries from greater Seattle and around the country.