Gale Lab



Systems Immunogenetics of Biodefense in the Collaborative Cross


The Gale Lab is partnering with Dr. Ralph Baric and Dr. Mark Heise of the University of North Carolina at Chapel Hill, and others, to develop new--genetically defined mouse models to mechanistically define the role of specific polymorphic genes and sets of genes in differentially regulating targeted immune responses.  
Individual Research Projects:
Project 1:
Dr. Ralph S. Baric
System Immunogenetics of SARS-CoV Infection

Project 2:
Dr. Mark Heise
System Immunogenetics of Influenza-Induced Innate & Adaptive Immunity in the Lung

Project 3:
Dr. Michael Gale, Jr.
System Immunogenetics of Innate Immune and Inflammatory Responses to West Nile Virus Infection

Project 4:
Dr. Jennifer Lund
System Immunogenetics of West Nile Virus Infection: Adaptive Immunity

Core A:
Dr. Ralph S. Baric
Administrative and Education Core

Core B:
Dr. Fernando Pardo-Manuel de Villena
Animal Models Core

Core C:
High-Throughput Molecular Profiling Core

Core D:
Dr. Shannon McWeeney
Systems Immunogenetics Core

Core E:
Bioinformatics Core
UNC Systems Genetics Core