Gale Lab

  RESEARCH CENTERS AND ASSOCIATED PROGRAMS  

 

NIH IMVC Program

 

The Center for the Study of Immune Mechanisms of Flavivirus Control is supported by the NIH and is comprised of 4 projects and two cores, integrated into a program of study aimed at defining the immune mechanisms that control West Nile virus infection. These unique projects feature comparative analyses of the emergent, virulent strain of WNV and a non-emergent, avirulent WNV strain. Results from these studies are providing novel insights to gu ide vaccine and therapeutic strategies aimed at modulating flavivirus infection.

  Project 1:
Dr. Michael Gale, Jr., Project Leader
Pathogen recognition and induction of innate immunity and inflammation against flavivirus infection

Administrative Core:
Dr. Michael Gale, Jr
., Core Leader

Gale Lab

UW School of Medicine

 
 

Project 2:
Dr. Michael S. Diamond & Dr. Robyn Klein, Dual Project Leaders
CNS innate immune control of flavivirus

WU School of Medicine  

Project 3:
Dr. Edward Clark
, Project Leader
Innate immune programming of humoral immunity to flaviviruses

Mouse Resources Core:
Dr. Edward Clark
, Core Leader

UW School of Medicine
Project 4:
Dr. Mehul Suthar, Project Leader
RIG-I-like receptor regulation of T cell immunity against flavivirus infection

Emory University Vaccine Center

   
NIH
 

West Nile and Dengue virus Information:

 
Washington State Department of Health: WNV CDC: Dengue  
EPA: WNV NBII: WNV  
MedlinePlus CDC: West Nile Virus  
Related Pages: West Nile Virus, The Host Response to West Nile virus

UNIVERSITY OF WASHINGTON