| |
| Center for the Study of Immune Mechanisms of Flavivirus Control | Hepatitis C Cooperative Research Center PNWRCE | Innate Immune Adjuvant Discovery | Systems Immunogenetics |
The Center for the Study of Innate Immunity and Hepatitis C Infection, is a component of the Hepatitis C Cooperative Research Centers funded by the NIH. The center is comprised of three translational research projects. The shared goal of these sites is to develop understanding of the virus/host interactions of hepatitis C virus (HCV) that regulate innate immunity, therapy, and the outcome of infection. These efforts are providing novel insights to guide the design of improved therapeutic strategies and vaccine approaches aimed at modulating HCV infection and immunity. |
 |
Our studies are focused on: Defining the viral and host genetic determinants that confer pathogen recognition of HCV, regulate hepatic innate immune triggering, and mediate effector and evasion responses during infection. Defining the HCV/host interactions that drive hepatic IFN production and response between hepatocytes and liver dendritic cells to control HCV infection. |
| Project 1: Dr. Michael Gale Jr. Pathogen signaling and innate immune control by HCV
|
|
||
 |
|||
 |
|
Administrative Core Clinical Core |
Hepatitis C Information: |
|
|
|
 |
 |
 |
