William R.A. Osborne

William R.A. Osborne, PhD

Research Professor (Emeritus)

Director, Osborne Lab

University of Washington
Box 358055
Seattle, WA 98195-8055
Phone: 206 685-3315
Email: wosborne@u.washington.edu

Dr. Osborne's current research is in two areas. The first is developing gene transfer therapies to treat cyclic neutropenia in dogs. This research entails the in vivo lentivirus-mediated delivery of canine granulocyte/colony stimulating factor and also its delivery using encapsulated cells. The second area is in gene therapy to treat Type 1 diabetes. This work entails the development of specific cell lines to secrete insulin and glucagon like peptide 1 for transplantation into diabetic rats. It also involves developing methods permitting implantation of allogeneic islet cells for long-term survival and therapy not requiring immunosuppression. Additionally, Dr. Osborne is collaborating with Dr. Ake Lernmark to develop lentivirus-mediated gene therapy to treat rats with type 1 diabetes. He is a member of the Scientific Editorial Board for Human Gene Therapy; he is also a member of the Musculoskeletal Tissue Engineering Study Section at the NIH, and he is also a member of the Scientific Review Board for the National Gene Vector Laboratories also based at the NIH. He has trained numerous post-doctoral fellows in the past, most of whom have gone on to have successful academic positions.

Faculty and Staff Directory

Division Chief

Bamshad, Michael J., MD


Adam, Margaret L.P., MD
Beck, Anita E., MD, PhD
Beier, David Randolph, MD, PhD
Dobyns, William B., MD
Doherty, Daniel A., MD, PhD
Glass, Ian A., MD, MB ChB
Hahn, Sihoun, MD, PhD
Hing, Anne V., MD
Johnson, Rebecca H., MD
Mefford, Heather C., MD, PhD
Merritt, J. Lawrence, MD
Millen, Kathleen J., PhD
Miller, Daniel G., MD, PhD
Mirzaa, Ghayda, MD
Osborne, William R.A., PhD
Pagon, Roberta A., MD
Scott, C. Ronald, MD
Sun, Angela, MD
Wallace, Stephanie E., MD


Aldinger, Kim, PhD
Carvill, Gemma, PhD
Chong, Jessica X, PhD
Gallego, Jabier, PhD
Geister, Krista, PhD
Ha, Seungshin, PhD
Myers, Candace, PhD
O'Day, Diana, PhD
Yu, Joon-Ho, MPH, PhD

Advanced Registered Nurse Practitioners

Earl, Dawn L., ARNP
Hale, Susan L., MN, ARNP

Genetic Counselors

Conta, Jessie, MS, CGC
Golden-Grant, Katie L, MS, CGC
Jamal, Seema M., MSc, CGC, CCGC
Ramsdell, Linda, MS, CGC
Schubert, Penny, MS, CGC
Sternen, Darci, MS, CGC
Uhrich, Stefanie, MS, CGC

Research Staff

Amell, Amanda M., BS
Bacus, Tamara J., BS
Bofferding, Kathryn, BS
Buckingham, Kati, BS
Buroker, Norman E., PhD
Cook, Joseph, MS
Dempsey, Jennifer C., MPH
Elliott, Susan E.
Frasher, Vicki A.
Garretson, Janet, MSW
Gildersleeve, Heidi, MS
Harrell, Tanya, BS
Heard, Jeff, BS
Heffernan, Janie, MS, RD
Huang, Jie-Yu, PhD
Lam, Jennfier P., MS
McMillin, Maggie J., BS
Musick, Katie, BA
Ogata, Beth, MS, RD, CSP
Person, Richard E.
Petek, Lisa, BS
Phelps, Ian, BS
Ragothaman, Kevin, BS
Shanker, Aditi, BA
Trahms, Cristine M., MS, RD
Wu, Zaining

Division Administrative Staff

Chin, Eileen, BA (Acc)
Sun , Amy