R1 DNA Structure and Properties
• Chapter 10, pp. 274-293 , William Klug and Michael Cummings,
"Concepts of Genetics." 45h ed., Prentice-Hall, Inc.,
1997
R2 Mapping by Meiotic Recombination
• Chapter 5, pp. 123-144 , Griffiths and others,"Introduction
to Genetic Analysis." 6th ed., W. H. Freeman Co., 1996.
R3 Cloning Bacterial Genes by Complementation
• Adapted from Stanley Bower and others, "Cloning,
sequencing, and characterization of the Bacillus subtilis
biotin biosynthetic operon." J. Bacteriology vol. 178
(1996) pages 4122- 4130.
R4 Bacterial Virus Genetics
• Walton L. Fangman, "Complementation and intragenic
recombination with a bacterial virus."
R5 Mutations in a Human Gene Resulting in Stops, Frameshifts
and a Splicing Defect
• Adapted from Anna Maria Barbieri and others, "Seven
novel additional small mutations and a new alternative splicing
in the human dystrophin gene ......" Eur. J. Human Genet.
vol. 4 (1996) pages 183-187.
R6 Meiotic Linkage Analysis with Human Pedigrees
• Natalie Angier, "Scientists zero in on gene tied
to prostate cancer." The New York Times, November 22, 1996.
• Walton L. Fangman and Katherine Kolor, "Quantitative
analysis of linkage with human pedigrees."
R7 Cloning and Sequence Analysis of a Human Disease Gene
• Adapted from Toshio Mochizuki and others, "PDK2,
a gene for polycystic kidney disease that encodes an integral
membrane protein." Science vol. 272 (1996) pages 1339-1342.
R8 Mitochondrial DNA Inheritance
• An article relevant to this topic will be handed-out
if an appropriate one is found.
R9 Analysis of a Bacterial Promoter
• Adapted from Teresa J. Kenny and Gordon Churchward, "Genetic
analysis of theMycobacterium smegmatis rpsL promoter."
J. Bacteriology vol. 178 (1996) pages 3564- 3571.
R10 Regulation of a Bacterial Gene
• Adapted from Frieder Schock and Michael Dahl, "Expression
of the tre operon of Bacillus subtilis 168 is
regulated by the repressor TreR." J. Bacteriology vol.
178 (1996) pages 4576-4581.
R11 Mutations Causing Defects in Human Development
• Adapted from Yatsuteru Muragaki and others, "Altered
growth and branching patterns in synpolydactyly caused by mutations
in HOXD13." Science vol. 272 (1996) pages 548-551.