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Archive of messages in the Genetics 453 newsgroup
Article: 1 of uwash.class.genet453
Path: news.u.washington.edu!evolution.genetics.washington.edu!joe
From: joe@evolution.genetics.washington.edu (Joe Felsenstein)
Newsgroups: uwash.class.genet453
Subject: Howdy
Date: 3 Jan 1996 18:57:13 GMT
Organization: University of Washington Genetics
Lines: 21
Message-ID: <4ceji9$am5@nntp3.u.washington.edu>
NNTP-Posting-Host: evolution.genetics.washington.edu
Summary: Introductory message
Keywords: Genetics 453
Hello! This is the newsgroup for Genetics 453 at the University of
Washington. Members of the class are encouraged to post questions,
comments, information, anything, as long as its on-topic and not
offensive. These can be addressed to me or to each other.
Please keep in mind that you must obey the rules of the
University of Washington about use and abuse of computing resources.
Also, check out the class World Wide Web site:
http://weber.u.washington.edu/~genetics/courses/genet453/genet453.html
(that's a "tilde" in there before genetics).
Messages posted here will not expire until the end of the quarter, and
most will also be archived in a file accessible through the Web site.
J.F.
--
Joe Felsenstein joe@genetics.washington.edu (IP No. 128.95.12.41)
Dept. of Genetics, Univ. of Washington, Box 357360, Seattle, WA 98195-7360 USA
Article: 2 of uwash.class.genet453
Path: news.u.washington.edu!pisces.fish.washington.edu!jon
From: Jon Baker
Newsgroups: uwash.class.genet453
Subject: Downloading the Pop Gen Sim
Date: Fri, 12 Jan 1996 15:02:02 -0800
Organization: University of Washington
Lines: 7
Message-ID:
NNTP-Posting-Host: pisces.fish.washington.edu
Mime-Version: 1.0
Content-Type: TEXT/PLAIN; charset=US-ASCII
After downloading the simul386.exe file and the simul8.doc file we had to
put the dos4gw.exe in the same directory as the others. Not in the root
file as in the directions. Hope this helps.
Jon
Article: 3 of uwash.class.genet453
Path: news.u.washington.edu!evolution.genetics.washington.edu!joe
From: joe@evolution.genetics.washington.edu (Joe Felsenstein)
Newsgroups: uwash.class.genet453
Subject: Re: Downloading the Pop Gen Sim
Date: 13 Jan 1996 00:12:46 GMT
Organization: University of Washington Genetics
Lines: 15
Message-ID: <4d6tdu$103@nntp3.u.washington.edu>
References:
NNTP-Posting-Host: evolution.genetics.washington.edu
Summary: DOS4GW.exe location
In article ,
Jon Baker wrote:
>
>After downloading the simul386.exe file and the simul8.doc file we had to
>put the dos4gw.exe in the same directory as the others. Not in the root
>file as in the directions. Hope this helps.
Thanks, I have heard that from people using dos4gw.exe in another context
and had failed to mention that, if it doesn't work in the root directory
(C:\), try it in the same directory as the simul386.exe program.
J.F.
--
Joe Felsenstein joe@genetics.washington.edu (IP No. 128.95.12.41)
Dept. of Genetics, Univ. of Washington, Box 357360, Seattle, WA 98195-7360 USA
Article: 5 of uwash.class.genet453
Path: news.u.washington.edu!evolution.genetics.washington.edu!joe
From: joe@evolution.genetics.washington.edu (Joe Felsenstein)
Newsgroups: uwash.class.genet453
Subject: My office hours this week -- a bit altered
Date: 22 Jan 1996 07:35:33 GMT
Organization: University of Washington Genetics
Lines: 7
Message-ID: <4dveo5$6rh@nntp3.u.washington.edu>
NNTP-Posting-Host: evolution.genetics.washington.edu
Summary: Friday at 2 not Thursday at 2, this time
Keywords: office hours
This week my office hours will be a bit different owing to a conflict.
They will be Friday from 2-3 instead of Thursday from 2-3. Next week
(i.e. on February 1) they go back to Thursday.
--
Joe Felsenstein joe@genetics.washington.edu (IP No. 128.95.12.41)
Dept. of Genetics, Univ. of Washington, Box 357360, Seattle, WA 98195-7360 USA
Article: 6 of uwash.class.genet453
Path: news.u.washington.edu!evolution.genetics.washington.edu!joe
From: joe@evolution.genetics.washington.edu (Joe Felsenstein)
Newsgroups: uwash.class.genet453
Subject: Date and time of final exam
Date: 22 Jan 1996 13:02:21 GMT
Organization: University of Washington Genetics
Lines: 9
Sender: Joe Felsenstein
Message-ID: <4e01st$1d9@nntp3.u.washington.edu>
NNTP-Posting-Host: evolution.genetics.washington.edu
Summary: Wednesday, March 13 at 2:30
Keywords: final exam, date, time
For those of you who have not read the Time Schedule in great detail, I should
point out when the final exam will be. It will be from 2:30-4:20 on Wednesday,
March 13, in a room to be determined. I will try to get a big enough room
for both the final and the midterm, so that people don't have to sit
next to each other.
--
Joe Felsenstein joe@genetics.washington.edu (IP No. 128.95.12.41)
Dept. of Genetics, Univ. of Washington, Box 357360, Seattle, WA 98195-7360 USA
From jonand@u.washington.edu Thu Feb 1 14:07:51 PST 1996
Article: 7 of uwash.class.genet453
Path: news.u.washington.edu!homer09.u.washington.edu!jonand
From: Jon Anderson
Newsgroups: uwash.class.genet453
Subject: Natural Selection
Date: Wed, 24 Jan 1996 10:58:38 -0800
Organization: University of Washington
Lines: 16
Message-ID:
NNTP-Posting-Host: homer09.u.washington.edu
Mime-Version: 1.0
Content-Type: TEXT/PLAIN; charset=US-ASCII
NNTP-Posting-User: jonand
Can anything be said about differences in natural selection in
"Primitive" societies vs "Modern" societies?
A rare locus which decreases the fitness of an individual may be
maintained within the population for many generations, but would it be
maintained in the modern society longer due to more medical intervention
which may increase the fitness of the individual?
Just something to think about-
______________________________________________________________________________
Jon Anderson jonand@u.washington.edu
University of Washington Phone: 616-4536
Center for Bioengineering/Molecular Biotechnology Fax: 685-7344
Seattle, WA 98195 Mail Stop: 357730
From joe@evolution.genetics.washington.edu Thu Feb 1 14:08:05 PST 1996
Article: 8 of uwash.class.genet453
Path: news.u.washington.edu!evolution.genetics.washington.edu!joe
From: joe@evolution.genetics.washington.edu (Joe Felsenstein)
Newsgroups: uwash.class.genet453
Subject: Re: Natural Selection
Date: 26 Jan 1996 01:47:54 GMT
Organization: University of Washington Genetics
Lines: 34
Message-ID: <4e9bsa$p0o@nntp3.u.washington.edu>
References:
NNTP-Posting-Host: evolution.genetics.washington.edu
Summary: Yes, but not much of an effect
In article ,
Jon Anderson wrote:
> Can anything be said about differences in natural selection in
>"Primitive" societies vs "Modern" societies?
> A rare locus which decreases the fitness of an individual may be
>maintained within the population for many generations, but would it be
>maintained in the modern society longer due to more medical intervention
>which may increase the fitness of the individual?
Well, I think you mean a rare allele, not a rare locus. Yes, if selection
against the allele is relaxed, it will increase in the population. But
not very quickly. There have been some nice papers on this -- the most
accessible is probably Jim Crow's paper:
Crow, J. F.
The quality of people: human evolutionary changes
Bioscience 16: 863-867 1966
Basically, if the gene was in equilibrium between mutation and selection,
each generation enough copies were removed from the population by selection
to compensate for the mutation rate, u. So when selection stops totally,
all that happens is that the gene frequency increases by u per generation.
That will, in most cases, be a very small percentage increase in the gene
frequency. Calculate a case or two and you will see.
For a recessive lethal gene, if the gene frequency is, say 0.0001, with
mutation rate 10 to the -8, then in the next generation after selection
ceases, the new gene frequency is 0.00010001.
J.F.
--
Joe Felsenstein joe@genetics.washington.edu (IP No. 128.95.12.41)
Dept. of Genetics, Univ. of Washington, Box 357360, Seattle, WA 98195-7360 USA
From joe@evolution.genetics.washington.edu Thu Feb 1 14:08:20 PST 1996
Article: 9 of uwash.class.genet453
Path: news.u.washington.edu!evolution.genetics.washington.edu!joe
From: joe@evolution.genetics.washington.edu (Joe Felsenstein)
Newsgroups: uwash.class.genet453
Subject: Guest lecture Monday 1/29
Date: 28 Jan 1996 15:52:21 GMT
Organization: University of Washington Genetics
Lines: 7
Message-ID: <4eg63l$jig@nntp3.u.washington.edu>
NNTP-Posting-Host: evolution.genetics.washington.edu
Summary: Mary Kuhner will speak on the HL-A locus
The guest lecture on Monday, January 29, will be given by Mary Kuhner of
the Genetics Department. She will talk about the human HL-A transplantation
antigen locus and its variation.
--
Joe Felsenstein joe@genetics.washington.edu (IP No. 128.95.12.41)
Dept. of Genetics, Univ. of Washington, Box 357360, Seattle, WA 98195-7360 USA
From joe@evolution.genetics.washington.edu Thu Feb 1 14:08:34 PST 1996
Article: 10 of uwash.class.genet453
Path: news.u.washington.edu!evolution.genetics.washington.edu!joe
From: joe@evolution.genetics.washington.edu (Joe Felsenstein)
Newsgroups: uwash.class.genet453
Subject: Review session
Date: 1 Feb 1996 19:42:20 GMT
Organization: University of Washington Genetics
Lines: 7
Message-ID: <4er52s$3e6@nntp3.u.washington.edu>
NNTP-Posting-Host: evolution.genetics.washington.edu
Summary: Friday at 2
There will be a review session on Friday at 2pm-3pm (in addition to the
regular lecture that day). It will be in J280. Come and bring your
questions.
--
Joe Felsenstein joe@genetics.washington.edu (IP No. 128.95.12.41)
Dept. of Genetics, Univ. of Washington, Box 357360, Seattle, WA 98195-7360 USA
From joe@evolution.genetics.washington.edu Thu Feb 1 14:08:51 PST 1996
Article: 11 of uwash.class.genet453
Path: news.u.washington.edu!evolution.genetics.washington.edu!joe
From: joe@evolution.genetics.washington.edu (Joe Felsenstein)
Newsgroups: uwash.class.genet453
Subject: Midterm on Monday the 5th
Date: 1 Feb 1996 19:46:00 GMT
Organization: University of Washington Genetics
Lines: 10
Message-ID: <4er59o$3k9@nntp3.u.washington.edu>
NNTP-Posting-Host: evolution.genetics.washington.edu
Summary: Midterm Monday the 5th, somewhere
We're trying to get another room for the midterm on Monday (at 11:30).
I will post the location here, on the course web site, and announce it
in class Friday. Stay tuned for its location.
If you don't get the word in time, come to J280 a bit early and we will
have a notice posted there (but allow for time to get to the new room!).
--
Joe Felsenstein joe@genetics.washington.edu (IP No. 128.95.12.41)
Dept. of Genetics, Univ. of Washington, Box 357360, Seattle, WA 98195-7360 USA
From joe@evolution.genetics.washington.edu Thu Feb 1 14:13:22 PST 1996
Article: 12 of uwash.class.genet453
Path: news.u.washington.edu!evolution.genetics.washington.edu!joe
From: joe@evolution.genetics.washington.edu (Joe Felsenstein)
Newsgroups: uwash.class.genet453
Subject: Re: Midterm on Monday the 5th
Date: 1 Feb 1996 22:00:40 GMT
Organization: University of Washington Genetics
Lines: 7
Message-ID: <4erd68$b2u@nntp3.u.washington.edu>
References: <4er59o$3k9@nntp3.u.washington.edu>
NNTP-Posting-Host: evolution.genetics.washington.edu
Summary: Midterm is Monday at 11:30 in D-209 HSB
The midterm on Monday (at 11:30) will be in D-209 Health Sciences
Building. That is in the dental school wing of Health Sciences,
on the second floor.
--
Joe Felsenstein joe@genetics.washington.edu (IP No. 128.95.12.41)
Dept. of Genetics, Univ. of Washington, Box 357360, Seattle, WA 98195-7360 USA
From roach@u.washington.edu Tue Mar 5 17:43:44 PST 1996
Article: 13 of uwash.class.genet453
Path: news.u.washington.edu!roach
From: roach@u.washington.edu (Jared Roach)
Newsgroups: uwash.class.genet453
Subject: Free Book: Origin of Species
Date: 7 Feb 1996 03:23:42 GMT
Organization: University of Washington, Seattle
Lines: 10
Distribution: uw
Message-ID: <4f95vu$6be@nntp3.u.washington.edu>
NNTP-Posting-Host: homer08.u.washington.edu
NNTP-Posting-User: roach
I have a 1904 edition of the Origin of Species which I no longer
have desk space for. Would anyone like it?
__________________________________________
Jared Roach
roach@u.washington.edu
From joe@evolution.genetics.washington.edu Tue Mar 19 07:51:38 PST 1996
Article: 14 of uwash.class.genet453
Path: news.u.washington.edu!evolution.genetics.washington.edu!joe
From: joe@evolution.genetics.washington.edu (Joe Felsenstein)
Newsgroups: uwash.class.genet453
Subject: Final exam time and place
Date: 6 Mar 1996 01:44:00 GMT
Organization: University of Washington Genetics
Lines: 6
Message-ID: <4hiql0$2hs@nntp3.u.washington.edu>
NNTP-Posting-Host: evolution.genetics.washington.edu
Summary: March 13 at 2:30 in J280
The final exam will take place on Wednesday, March 13, at 2:30-4:20 pm, in
J280 Health Sciences (our usual lecture room).
--
Joe Felsenstein joe@genetics.washington.edu (IP No. 128.95.12.41)
Dept. of Genetics, Univ. of Washington, Box 357360, Seattle, WA 98195-7360 USA
From joe@evolution.genetics.washington.edu Tue Mar 19 07:52:11 PST 1996
Article: 15 of uwash.class.genet453
Path: news.u.washington.edu!evolution.genetics.washington.edu!joe
From: joe@evolution.genetics.washington.edu (Joe Felsenstein)
Newsgroups: uwash.class.genet453
Subject: Review session
Date: 6 Mar 1996 01:45:17 GMT
Organization: University of Washington Genetics
Lines: 6
Message-ID: <4hiqnd$2is@nntp3.u.washington.edu>
NNTP-Posting-Host: evolution.genetics.washington.edu
Summary: On Friday the 8th at 3:00-4:30
There will be a review session on Friday, March 8, at 3:00-4:30 in room
J280 HSB (the usual lecture room).
--
Joe Felsenstein joe@genetics.washington.edu (IP No. 128.95.12.41)
Dept. of Genetics, Univ. of Washington, Box 357360, Seattle, WA 98195-7360 USA
From joe@evolution.genetics.washington.edu Tue Mar 19 07:51:50 PST 1996
Article: 16 of uwash.class.genet453
Path: news.u.washington.edu!evolution.genetics.washington.edu!joe
From: joe@evolution.genetics.washington.edu (Joe Felsenstein)
Newsgroups: uwash.class.genet453
Subject: The grades and exams
Date: 17 Mar 1996 16:14:02 GMT
Organization: University of Washington Genetics
Lines: 17
Message-ID: <4ihdoa$38@nntp3.u.washington.edu>
NNTP-Posting-Host: evolution.genetics.washington.edu
Summary: They're available as of Monday
Keywords: unpleasant chore
The grading in Genetics 453 is completed. The final exams, on which
your point totals and grades are marked too, will be available from
the Department Office (J205 HSB) as of Monday morning. See the
secretary in the desk nearest the door (he's new so I don't know his name).
The point and grade distribution will be posted in the next news message
in this newsgroup and will be posted outside of J205.
Thanks for putting up with a certain amount of nonsense.
(Joe Miller -- please contact me if there has been a mixup concerning
your grades.)
Joe
--
Joe Felsenstein joe@genetics.washington.edu (IP No. 128.95.12.41)
Dept. of Genetics, Univ. of Washington, Box 357360, Seattle, WA 98195-7360 USA
From joe@evolution.genetics.washington.edu Tue Mar 19 07:51:57 PST 1996
Article: 17 of uwash.class.genet453
Path: news.u.washington.edu!evolution.genetics.washington.edu!joe
From: joe@evolution.genetics.washington.edu (Joe Felsenstein)
Newsgroups: uwash.class.genet453
Subject: Point and grade distribution
Date: 17 Mar 1996 16:16:25 GMT
Organization: University of Washington Genetics
Lines: 29
Message-ID: <4ihdsp$47@nntp3.u.washington.edu>
NNTP-Posting-Host: evolution.genetics.washington.edu
Summary: The point and grade distribution
Distribution of total scores (midterm+homework+final) in Genetics 453
(each "-" covers a 3-point range centered at the score on the scale.
indication of grades is given too)
3.5
2.0 2.3 2.8 3.0 3.3 ! 3.8 4.0
! ! ! ! ! ! ! !
M
M
M M M
M M M M
M M MMM M M
M M M M MMMMMM M M M M
----------------------------------------------------------
^ ^ ^ ^ ^ ^ ^
150 180 210 240 270 300 325
Here are the actual point totals, sorted:
159 180 216 217 227 254 254 254 256 259
260 263 264 264 265 268 268 269 269 271
276 281 281 283 283 283 283 288 288 303
--
Joe Felsenstein joe@genetics.washington.edu (IP No. 128.95.12.41)
Dept. of Genetics, Univ. of Washington, Box 357360, Seattle, WA 98195-7360 USA