Genetics 562 Population Genetics Spring, 1999 J. Felsenstein Syllabus Date Topic Reading 3/29 Introduction; Hardy-Weinberg proportions I.1-I.3 3/30 " " (P. Beerli) " " 3/31 Multiple alleles, difft. sexes (P. Beerli) I.4, I.6 4/2 Sex-linkage (M. Kuhner) I.7 5 Linkage and linkage disequilibrium I.8 6, 7 Natural Selection II.1-II.2 9 " " II.4, II.5 12 Polymorphisms and fitness II.6-II.8 13 " " " II.9-II.11 14 " " " " " 16 Kin, group and species selection II.12 19 Mutation III.1-III.3 20, 21 Maintenance of deleterious mutants III.4-III.6 23 Migration, Clines IV.1-IV.11 26, 27 " " " " 28, 30 Inbreeding in pedigrees V.1-V.5 5/3, 4 Regular systems of mating V.10-V.12, V.14 5 Inbreeding depression V.13 7 Genetic drift VI.1-VI.4 10 " " " " 11 Effective population size VI.5-VI.7 12, 14 Neutral mutation theory VII.1-VII.2 17 Repeated sequences none 18 Trees of genes X.2 19, 21 Molecular evolution VII.7, VII.8 24, 25 Drift and other forces VII.4,VII.5,VII.8,VII.9 26 Drift and other forces " " " " 28 Genetics of quantitative characters IX.1-IX.5 31 HOLIDAY (Memorial Day; Folk Life Festival) 6/1 Genetics of quantitative characters " " 2 Components of variance, selection response IX.6-IX.9 4 Finding QTLs (none) Text: Theoretical Evolutionary Genetics, by Joe Felsenstein ($16-$18 or so at ASUW Publishing, HUB) Course web page: http://depts.washington.edu/genetics/courses/genet562/1999 Course newsgroup: uwash.class.genet562