Syllabus

    

Date		Topic		Reading
March 31		Introduction; Hardy-Weinberg proportions		I.1-I.3
April 2		Multiple alleles, difft. sexes		I.4, I.6
4		Sex-linkage		I.7
7		Linkage and linkage disequilibrium		I.8
9		Natural Selection		II.1-II.2
11		" "		II.4, II.5
14		Polymorphisms and fitness		II.6-II.8
16		" " "		II.9-II.11
18		Kin, group and species selection		II.12
21		Mutation		III.1-III.3
23		Maintenance of deleterious mutants		III.4-III.6
25		Migration, Clines		IV.1-IV.11
28		" "		" "
30		Inbreeding in pedigrees		V.1-V.5
May 2		Regular systems of mating		V.10-V.12, V.14
5		Inbreeding depression		V.13
7		Genetic drift		VI.1-VI.4
9		Effective population size (guest lecturer: Mary Kuhner)		VI.5-VI.7
12		Neutral mutation theory		VII.1-VII.2
14		Trees of genes		X.2
16		Trees of genes II -- the sequel		" "
19		Molecular evolution		VII.7, VII.8
21		Drift and other forces		VII.4,VII.5,VII.8,VII.9
23		Drift and other forces		" " " "
26		HOLIDAY (Memorial Day; last day of Folk Life Festival)
28		Genetics of quantitative characters		IX.1-IX.5
30		Components of variance		IX.6-IX.9
6/2		Selection response		" "
4		Finding QTLs		(none)
6		Finding QTLs		(none)

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Homeworks will be assigned each week, to be turned in the next week.

Exams: none.

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Text: Theoretical Evolutionary Genetics, by Joe Felsenstein, publication to be arranged, hopefully about $25

The text is also available as a PDF that can be downloaded:
from this link

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Course web page: http://depts.washington.edu/genetics/courses/genet562/2003