Christine K. Abrass, M.D., F.A.C.P.
Research Interests: My research has examined the mechanisms of initiation and transition to progression of kidney disease with a specific focus on diabetic nephropathy and the nephropathy associated with aging. Using tools of cell and molecular biology, we have established that early changes in composition of the extracellular matrix influence and perpetuate the altered function of glomerular cells following kidney injury. Current studies are investigating the role changes in laminin isoform expression that accompany microvascular changes that begin in middle age, and the alterations in mRNA translation that lead to this change in protein composition of the extracellular matrix.
Board Certifications: Internal Medicine, Nephrology
Education and Training:
College: 1969, Denison University, Granvile, OH
Medical School: 1973, Case Western Reserve University
Internship: 1973-1974, University of California, San Diego
Residency: 1974-1976, University of California, San Diego; Mercer Hospital and Medical Center, San Diego
Fellowship: 1976-1979, Harbor-UCLA Medical Center, Torrance, CA
Publications: Go to PubMed.
General Information: Email Dr. Abrass.